Literature DB >> 26872795

Spray drying of lipid-based systems loaded with Camellia sinensis polyphenols.

Vanessa A Secolin1, Claudia R F Souza1, Wanderley P Oliveira1.   

Abstract

In this work, spray-dried lipid systems based on soy phosphatidylcholine, cholesterol and lauroyl polyoxylglycerides for entrapping Green tea polyphenols were produced. The aim was to study the effects of the encapsulating composition and spray drying conditions on the system performance and physicochemical product properties. The spray dryer powder production yield falls around 50.7 ± 2.8%, which is typical for lab scale spray dryers. Wrinkled and rounded particles, with low surface porosities were generated, independent of the drying carriers (trehalose or lactose) used. The product showed high encapsulation efficiency of Green tea polyphenols, which was promptly redispersible in water. It presented low density, and good compressive and flow properties. The results herein reported confirm the feasibility of the entrapment of Green tea polyphenols in lipid-based compositions by spray drying in presence of the drying carriers evaluated. The spray-dried microparticles show high potential to be used as additive in food, nutraceutical and pharmaceutical products.

Entities:  

Keywords:  Bioavailability; Camellia sinensis; Green tea catechins; encapsulation; lipid systems; pro-liposome; spray drying

Mesh:

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Year:  2016        PMID: 26872795     DOI: 10.3109/08982104.2016.1140183

Source DB:  PubMed          Journal:  J Liposome Res        ISSN: 0898-2104            Impact factor:   3.648


  2 in total

1.  Spray-Dried Proliposomes: an Innovative Method for Encapsulation of Rosmarinus officinalis L. Polyphenols.

Authors:  Victor Oloruntoba Bankole; Michael Oluwole Osungunna; Claudia Regina Fernandes Souza; Sergio Luiz Salvador; Wanderley Pereira Oliveira
Journal:  AAPS PharmSciTech       Date:  2020-05-18       Impact factor: 3.246

2.  A Liposomal Formulation for Improving Solubility and Oral Bioavailability of Nifedipine.

Authors:  Ye Bi; Bingcong Lv; Lianlian Li; Robert J Lee; Jing Xie; Zhidong Qiu; Lesheng Teng
Journal:  Molecules       Date:  2020-01-14       Impact factor: 4.411

  2 in total

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