Literature DB >> 26872026

The Use of Vascularized Fascia as Carrier in Cases of Prelaminated Fasciocartilaginous and Osseofascial Flaps.

Myron Tsagarakis1, Georgia-Alexandra Spyropoulou2, Efstathios Lykoudis3, Apostolos Papalois4, Antonis Tsimponis2, Constantina Fragia5, Thomais Iconomou6, Othon Papadopoulos7.   

Abstract

Background This experimental study investigates the use of vascularized fascia as carrier for prelaminated cartilage and bone flaps. Methods A total of 30 male New Zealand white rabbits were divided into two equal groups (A and B). The fascia surrounding the inguinal fat and superficial inferior epigastric vessels was dissected. In group A, the fascia was wrapped around a template (20 × 40 mm) of cartilage harvested from the rabbit's ear. In group B, the fascia was wrapped around a 15 × 35 mm piece of rib cortical bone. After a maturation period of 4 weeks, group A was subdivided into three groups (A1, A2, and A3). In group A1 (six animals) the animals were sacrificed and the flaps were sent for histological examination, in A2 (six animals) the flaps were rotated 180 degrees and anchored at knee level, and in A3 (two animals) the flaps were transferred as free flaps to the right SIE (superficial inferior epigastric vessels). The animals of subgroups A2 and A3 were sacrificed after another maturation period of 2 weeks and the flaps were sent for histological examination. After a maturation period of 6 weeks, group B was subdivided into three subgroups (B1, B2, and B3) corresponding to the cartilage subgroups. Subgroups B2 and B3 were sacrificed after 2 weeks. Results All flaps of groups A and B demonstrated good viability apart from one specimen of subgroup B2. Angiogenesis was present in all groups. Conclusion Meticulously dissected vascularized fascia can be successfully used for prelamination of complex fasciocartilaginous or osseofascial flaps. The required maturation periods are 4 and 6 weeks, respectively. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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Year:  2016        PMID: 26872026     DOI: 10.1055/s-0035-1571250

Source DB:  PubMed          Journal:  J Reconstr Microsurg        ISSN: 0743-684X            Impact factor:   2.873


  2 in total

1.  Effect of tissue expansion on chondrocyte sheets in cartilage composite reconstruction.

Authors:  Chu-Hsin Chen; Peng Xu; Yahong Chen; Ke Xue; Kai Liu
Journal:  Am J Transl Res       Date:  2021-12-15       Impact factor: 4.060

Review 2.  [Research progress of in vivo bioreactor for bone tissue engineering].

Authors:  Jian Wang; Xiao Wang; Ping Zhen; Bo Fan
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2021-05-15
  2 in total

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