Literature DB >> 26871626

A New Way to Diversify Antibodies by DNA Transposition.

Davide F Robbiani1, Michel C Nussenzweig2.   

Abstract

While searching for new therapeutics against malaria, Lanzavecchia and colleagues discovered that antibodies can be diversified by DNA sequences encoded outside of antibody genes.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 26871626     DOI： 10.1016/j.cell.2016.01.031

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  2 in total

1.  Somatic Diversification of Rearranged Antibody Gene Segments by Intra- and Interchromosomal Templated Mutagenesis.

Authors:  Gordon A Dale; Daniel J Wilkins; Jordan Rowley; Christopher D Scharer; Christopher M Tipton; Jennifer Hom; Jeremy M Boss; Victor Corces; Ignacio Sanz; Joshy Jacob
Journal:  J Immunol       Date:  2022-04-13       Impact factor: 5.422

2.  Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.

Authors:  Kai Xu; Yiran Wang; Chen-Hsiang Shen; Yiwei Chen; Baoshan Zhang; Kevin Liu; Yaroslav Tsybovsky; Shuishu Wang; S Katie Farney; Jason Gorman; Tyler Stephens; Raffaello Verardi; Yongping Yang; Tongqing Zhou; Gwo-Yu Chuang; Antonio Lanzavecchia; Luca Piccoli; Peter D Kwong
Journal:  Nat Commun       Date:  2021-07-09       Impact factor: 14.919
  2 in total

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