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Literature DB >> 26864087

Quantitatively resolving multivalent interactions on a macroscopic scale using force spectroscopy.

Qiongzheng Hu¹, Haopeng Yang², Yuhong Wang², Shoujun Xu¹.

Abstract

Multivalent interactions remain difficult to be characterized and consequently controlled, particularly on a macroscopic scale. Using force-induced remnant magnetization spectroscopy (FIRMS), we have resolved the single-, double-, and triple-biotin-streptavidin interactions, multivalent DNA interactions and CXCL12-CXCR4 interactions on millimetre-scale surfaces. Our results establish FIRMS as a viable method for systematic resolution and controlled formation of multivalent interactions.

Entities: Chemical Gene Species

Mesh：

Substances：
Biotin
DNA
Streptavidin

Year: 2016 PMID： 26864087 PMCID： PMC4767602 DOI： 10.1039/c5cc10535h

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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