Literature DB >> 26863486

Regulatory T Cell Immunotherapy for Type 1 Diabetes: A Step Closer to Success?

Jagadeesh Bayry1, Jean-François Gautier2.   

Abstract

Regulatory T cell (Treg) therapy has shown promises in experimental models of type 1 diabetes (T1D) and other autoimmune diseases. Now, Bluestone et al. (2015) report in a phase 1, dose-escalation study that ex vivo-expanded autologous polyclonal Treg therapy is safe and well tolerated in adult patients with recent-onset T1D.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 26863486     DOI： 10.1016/j.cmet.2016.01.010

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  9 in total

Review 1.  Heart Failure with Preserved Ejection Fraction and Future Pharmacological Strategies: a Glance in the Crystal Ball.

Authors:  Carsten Tschöpe; Sophie Van Linthout; Behrouz Kherad
Journal:  Curr Cardiol Rep       Date:  2017-08       Impact factor: 2.931

Review 2.  Nanotechnology in cell replacement therapies for type 1 diabetes.

Authors:  Alexander U Ernst; Daniel T Bowers; Long-Hai Wang; Kaavian Shariati; Mitchell D Plesser; Natalie K Brown; Tigran Mehrabyan; Minglin Ma
Journal:  Adv Drug Deliv Rev       Date:  2019-02-02       Impact factor: 15.470

3.  Regulatory T cells ameliorate intracerebral hemorrhage-induced inflammatory injury by modulating microglia/macrophage polarization through the IL-10/GSK3β/PTEN axis.

Authors:  Kai Zhou; Qi Zhong; Yan-Chun Wang; Xiao-Yi Xiong; Zhao-You Meng; Ting Zhao; Wen-Yao Zhu; Mao-Fan Liao; Li-Rong Wu; Yuan-Rui Yang; Juan Liu; Chun-Mei Duan; Jie Li; Qiu-Wen Gong; Liang Liu; Mei-Hua Yang; Ao Xiong; Jian Wang; Qing-Wu Yang
Journal:  J Cereb Blood Flow Metab       Date:  2016-07-20       Impact factor: 6.200

4.  Identification of common key genes and pathways between type 1 diabetes and multiple sclerosis using transcriptome and interactome analysis.

Authors:  Nahid Safari-Alighiarloo; Mohammad Taghizadeh; Seyyed Mohammad Tabatabaei; Saeed Namaki; Mostafa Rezaei-Tavirani
Journal:  Endocrine       Date:  2020-01-07       Impact factor: 3.633

Review 5.  Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration.

Authors:  Jiatao Li; Jean Tan; Mikaël M Martino; Kathy O Lui
Journal:  Front Immunol       Date:  2018-03-23       Impact factor: 7.561

6.  Tolerogenic vaccine composited with islet-derived multipeptides and cyclosporin A induces pTreg and prevents Type 1 diabetes in murine model.

Authors:  Xian Zhou; Shijie Zhang; Fan Yu; Gan Zhao; Shuang Geng; Wencong Yu; Xuan-Yi Wang; Bin Wang
Journal:  Hum Vaccin Immunother       Date:  2019-10-23       Impact factor: 3.452

7.  Quantitative increase in T regulatory cells enhances bone remodeling in osteogenesis imperfecta.

Authors:  In-Hong Kang; Uday K Baliga; Shilpak Chatterjee; Paramita Chakraborty; Seungho Choi; Nathan Buchweitz; Hong Li; Yongren Wu; Hai Yao; Shikhar Mehrotra; Meenal Mehrotra
Journal:  iScience       Date:  2022-08-05

Review 8.  Progress in Liver Transplant Tolerance and Tolerance-Inducing Cellular Therapies.

Authors:  Xiaoxiao Du; Sheng Chang; Wenzhi Guo; Shuijun Zhang; Zhonghua Klaus Chen
Journal:  Front Immunol       Date:  2020-06-24       Impact factor: 7.561

9.  Benefit of Belatacept in Cord Blood-Derived Regulatory T Cell-Mediated Suppression of Alloimmune Response.

Authors:  Xing He; Sang Li; Juan Zhang; Lu Cao; Cejun Yang; Pengfei Rong; Shounan Yi; Kedar Ghimire; Xiaoqian Ma; Wei Wang
Journal:  Cell Transplant       Date:  2021 Jan-Dec       Impact factor: 4.064
  9 in total

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