Literature DB >> 26863441

Correction: Overexpression of MEOX2 and TWIST1 is Associated with H3K27me3 Levels and Determines Lung Cancer Chemoresistance and Prognosis.

Federico Ávila-Moreno, Leonel Armas-López, Aldo M Álvarez-Moran, Zoila López-Bujanda, Blanca Ortiz-Quintero, Alfredo Hidalgo-Miranda, Francisco Urrea-Ramírez, R María Rivera-Rosales, Eugenia Vázquez-Manríquez, Erika Peña-Mirabal, José Morales-Gómez, Juan C Vázquez-Minero, José L Téllez-Becerra, Roberto Ramírez-Mendoza, Alejandro Ávalos-Bracho, Enrique Guzmán de Alba, Karla Vázquez-Santillán, Vilma Maldonado-Lagunas, Patricio Santillán-Doherty, Patricia Piña-Sánchez, Joaquin Zúñiga-Ramos.   

Abstract

Entities:  

Year:  2016        PMID: 26863441      PMCID: PMC4749347          DOI: 10.1371/journal.pone.0146569

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


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In Fig 4, the statistical significance indicators are missing. Please see the corrected Fig 4 here.
Fig 4

Analysis of the enrichment profile of H3K27me3, H3K27ac and H3K4me3 at the MEOX2 and TWIST1 promoters in NSCLC patients.

(A) H3K27me3 enrichment in the MEOX2 promoter sequence (**Mann-Whitney U test, p≤0.01, and F test, p≤0.0003) and (B) H3K27me3 enrichment in the TWIST1 promoter sequence in high survival patients as compared to patients with poor prognoses (***Mann-Whitney U test,p≤0.01, and unpaired t-test, p≤0.02). (C) H3K27ac enrichment in the promoter sequence of MEOX2 (no significant changes) and (D) H3K27ac enrichment in the promoter sequence of TWIST1 in high survival patients compared to patients with poor prognoses (no significant changes). (E) H3K4me3 enrichment in the MEOX2 promoter sequence (*F test, p≤0.02) and (F) the TWIST1 promoter sequence in high survival patients compared to patients with poor prognoses (***F test, p≤0.0006). Error bars represent mean with range.

Analysis of the enrichment profile of H3K27me3, H3K27ac and H3K4me3 at the MEOX2 and TWIST1 promoters in NSCLC patients.

(A) H3K27me3 enrichment in the MEOX2 promoter sequence (**Mann-Whitney U test, p≤0.01, and F test, p≤0.0003) and (B) H3K27me3 enrichment in the TWIST1 promoter sequence in high survival patients as compared to patients with poor prognoses (***Mann-Whitney U test,p≤0.01, and unpaired t-test, p≤0.02). (C) H3K27ac enrichment in the promoter sequence of MEOX2 (no significant changes) and (D) H3K27ac enrichment in the promoter sequence of TWIST1 in high survival patients compared to patients with poor prognoses (no significant changes). (E) H3K4me3 enrichment in the MEOX2 promoter sequence (*F test, p≤0.02) and (F) the TWIST1 promoter sequence in high survival patients compared to patients with poor prognoses (***F test, p≤0.0006). Error bars represent mean with range.
  1 in total

1.  Overexpression of MEOX2 and TWIST1 is associated with H3K27me3 levels and determines lung cancer chemoresistance and prognosis.

Authors:  Federico Ávila-Moreno; Leonel Armas-López; Aldo M Álvarez-Moran; Zoila López-Bujanda; Blanca Ortiz-Quintero; Alfredo Hidalgo-Miranda; Francisco Urrea-Ramírez; R María Rivera-Rosales; Eugenia Vázquez-Manríquez; Erika Peña-Mirabal; José Morales-Gómez; Juan C Vázquez-Minero; José L Téllez-Becerra; Roberto Ramírez-Mendoza; Alejandro Ávalos-Bracho; Enrique Guzmán de Alba; Karla Vázquez-Santillán; Vilma Maldonado-Lagunas; Patricio Santillán-Doherty; Patricia Piña-Sánchez; Joaquin Zúñiga-Ramos
Journal:  PLoS One       Date:  2014-12-02       Impact factor: 3.240

  1 in total
  2 in total

1.  Identification of tumor microenvironment-related prognostic genes in colorectal cancer based on bioinformatic methods.

Authors:  Yi Liu; Long Cheng; Chao Li; Chen Zhang; Lei Wang; Jiantao Zhang
Journal:  Sci Rep       Date:  2021-07-22       Impact factor: 4.379

2.  Exploration of the diagnostic value and molecular mechanism of miR‑1 in prostate cancer: A study based on meta‑analyses and bioinformatics.

Authors:  Zu-Cheng Xie; Jia-Cheng Huang; Li-Jie Zhang; Bin-Liang Gan; Dong-Yue Wen; Gang Chen; Sheng-Hua Li; Hai-Biao Yan
Journal:  Mol Med Rep       Date:  2018-10-25       Impact factor: 2.952

  2 in total

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