Literature DB >> 26862399

Carbapenem resistance: overview of the problem and future perspectives.

Georgios Meletis.   

Abstract

Carbapenem resistance, mainly among Gram-negative pathogens, is an ongoing public-health problem of global dimensions. This type of antimicrobial resistance, especially when mediated by transferable carbapenemase-encoding genes, is spreading rapidly causing serious outbreaks and dramatically limiting treatment options. In this article, important key points related to carbapenem resistance are reviewed and future perspectives are discussed.

Entities:  

Keywords:  antibiotic resistance; carbapenemases; carbapenems

Year:  2016        PMID: 26862399      PMCID: PMC4735501          DOI: 10.1177/2049936115621709

Source DB:  PubMed          Journal:  Ther Adv Infect Dis        ISSN: 2049-9361


  61 in total

1.  Plasmid-mediated carbapenem-hydrolysing OXA-48 beta-lactamase in Klebsiella pneumoniae from Tunisia.

Authors:  Gaelle Cuzon; Thierry Naas; Aude Lesenne; Michel Benhamou; Patrice Nordmann
Journal:  Int J Antimicrob Agents       Date:  2010-03-30       Impact factor: 5.283

2.  Early dissemination of NDM-1- and OXA-181-producing Enterobacteriaceae in Indian hospitals: report from the SENTRY Antimicrobial Surveillance Program, 2006-2007.

Authors:  Mariana Castanheira; Lalitagauri M Deshpande; Dilip Mathai; Jan M Bell; Ronald N Jones; Rodrigo E Mendes
Journal:  Antimicrob Agents Chemother       Date:  2010-12-28       Impact factor: 5.191

Review 3.  IMP-type metallo-β-lactamases in Gram-negative bacilli: distribution, phylogeny, and association with integrons.

Authors:  Wei-Hua Zhao; Zhi-Qing Hu
Journal:  Crit Rev Microbiol       Date:  2011-03-29       Impact factor: 7.624

4.  Interplay of efflux system, ampC, and oprD expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates.

Authors:  John Quale; Simona Bratu; Jyoti Gupta; David Landman
Journal:  Antimicrob Agents Chemother       Date:  2006-05       Impact factor: 5.191

5.  Novel acquired metallo-beta-lactamase gene, bla(SIM-1), in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea.

Authors:  Kyungwon Lee; Jong Hwa Yum; Dongeun Yong; Hyuk Min Lee; Heung Dong Kim; Jean-Denis Docquier; Gian Maria Rossolini; Yunsop Chong
Journal:  Antimicrob Agents Chemother       Date:  2005-11       Impact factor: 5.191

Review 6.  OXA-48-like carbapenemases: the phantom menace.

Authors:  Laurent Poirel; Anaïs Potron; Patrice Nordmann
Journal:  J Antimicrob Chemother       Date:  2012-04-11       Impact factor: 5.790

7.  First Report of Ceftazidime-Avibactam Resistance in a KPC-3-Expressing Klebsiella pneumoniae Isolate.

Authors:  Romney M Humphries; Shangxin Yang; Peera Hemarajata; Kevin W Ward; Janet A Hindler; Shelley A Miller; Aric Gregson
Journal:  Antimicrob Agents Chemother       Date:  2015-07-20       Impact factor: 5.191

8.  Regional dissemination of KPC-producing Klebsiella pneumoniae.

Authors:  Brandon Kitchel; Daniel R Sundin; Jean B Patel
Journal:  Antimicrob Agents Chemother       Date:  2009-08-17       Impact factor: 5.191

9.  Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA.

Authors:  Andrea Endimiani; Andrea M Hujer; Federico Perez; Christopher R Bethel; Kristine M Hujer; Jennifer Kroeger; Margret Oethinger; David L Paterson; Mark D Adams; Michael R Jacobs; Daniel J Diekema; Gerri S Hall; Stephen G Jenkins; Louis B Rice; Fred C Tenover; Robert A Bonomo
Journal:  J Antimicrob Chemother       Date:  2009-01-20       Impact factor: 5.790

10.  New Delhi metallo-beta-lactamase from traveler returning to Canada.

Authors:  Gisele Peirano; Jasmine Ahmed-Bentley; Neil Woodford; Johann D Pitout
Journal:  Emerg Infect Dis       Date:  2011-02       Impact factor: 6.883

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  121 in total

1.  The Role of Gram-Negative Bacteria in Urinary Tract Infections: Current Concepts and Therapeutic Options.

Authors:  Payam Behzadi; Edit Urbán; Mária Matuz; Ria Benkő; Márió Gajdács
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

Review 2.  A literature review of perioperative antibiotic administration in surgery for medication-related osteonecrosis of the jaw.

Authors:  Masaya Akashi; Junya Kusumoto; Daisuke Takeda; Takashi Shigeta; Takumi Hasegawa; Takahide Komori
Journal:  Oral Maxillofac Surg       Date:  2018-10-16

3.  The Novel β-Lactam Enhancer Zidebactam Augments the In Vivo Pharmacodynamic Activity of Cefepime in a Neutropenic Mouse Lung Acinetobacter baumannii Infection Model.

Authors:  S S Bhagwat; H Periasamy; S S Takalkar; S R Palwe; H N Khande; M V Patel
Journal:  Antimicrob Agents Chemother       Date:  2019-03-27       Impact factor: 5.191

Review 4.  The rise and spread of mcr plasmid-mediated polymyxin resistance.

Authors:  Sue C Nang; Jian Li; Tony Velkov
Journal:  Crit Rev Microbiol       Date:  2019-05-23       Impact factor: 7.624

5.  DeepBL: a deep learning-based approach for in silico discovery of beta-lactamases.

Authors:  Yanan Wang; Fuyi Li; Manasa Bharathwaj; Natalia C Rosas; André Leier; Tatsuya Akutsu; Geoffrey I Webb; Tatiana T Marquez-Lago; Jian Li; Trevor Lithgow; Jiangning Song
Journal:  Brief Bioinform       Date:  2021-07-20       Impact factor: 11.622

6.  Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases.

Authors:  Orville A Pemberton; Priyadarshini Jaishankar; Afroza Akhtar; Jessie L Adams; Lindsey N Shaw; Adam R Renslo; Yu Chen
Journal:  J Med Chem       Date:  2019-09-13       Impact factor: 7.446

7.  In Vitro Activity Analysis of a New Polymyxin, SPR741, Tested in Combination with Antimicrobial Agents against a Challenge Set of Enterobacteriaceae, Including Molecularly Characterized Strains.

Authors:  Rodrigo E Mendes; Paul R Rhomberg; Troy Lister; Nicole Cotroneo; Thomas R Parr; Mariana Castanheira
Journal:  Antimicrob Agents Chemother       Date:  2020-12-16       Impact factor: 5.191

Review 8.  Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs.

Authors:  Natalia Molchanova; Paul R Hansen; Henrik Franzyk
Journal:  Molecules       Date:  2017-08-29       Impact factor: 4.411

9.  Potentiation of Antibiotic Activity by a Novel Cationic Peptide: Potency and Spectrum of Activity of SPR741.

Authors:  David Corbett; Andrew Wise; Tara Langley; Kirsty Skinner; Emily Trimby; Stephen Birchall; Alain Dorali; Stephanie Sandiford; Jennifer Williams; Peter Warn; Martti Vaara; Troy Lister
Journal:  Antimicrob Agents Chemother       Date:  2017-07-25       Impact factor: 5.191

10.  Dynamics of bla KPC-2 Dissemination from Non-CG258 Klebsiella pneumoniae to Other Enterobacterales via IncN Plasmids in an Area of High Endemicity.

Authors:  Ana M Rada; Elsa De La Cadena; Carlos Agudelo; Cesar Capataz; Nataly Orozco; Cristian Pallares; An Q Dinh; Diana Panesso; Rafael Ríos; Lorena Diaz; Adriana Correa; Blake M Hanson; Maria V Villegas; Cesar A Arias; Eliana Restrepo
Journal:  Antimicrob Agents Chemother       Date:  2020-11-17       Impact factor: 5.191

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