Literature DB >> 26862103

Authors' response.

Nihat Sayin1, Necip Kara, Gokhan Pekel, Hasan Altinkaynak.   

Abstract

Entities:  

Year:  2015        PMID: 26862103      PMCID: PMC4784086     

Source DB:  PubMed          Journal:  Indian J Ophthalmol        ISSN: 0301-4738            Impact factor:   1.848


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Dear Sir, We appreciate the interest in and comments of the author concerning our article.[1] As we addressed in our study, choroid has a very large vascular network and choroidal circulation has one of the highest rates of blood flow in humans.[1] However, an important physiological role for the high choroidal blood flow is to help temperature regulation of the retina.[23] Increased body temperature during exercise may lead to vasodilation and increase in choroidal blood flow.[4] On the other hand, the previous study showed that decreased retinal temperature led to a significant decrease in choroidal blood flow.[5] Our findings confirm the outcomes of that study. We found that choroidal thickness (CT) values increased significantly at 5 min following dynamic exercise and returned to baseline values at 15 min following the exercise. Core body temperature rises during exercise and returns to baseline values following the exercise.[6] In conclusion, high choroidal blood flow protects photoreceptors, retina pigment epithelium, and vitreous from heat stress.[7] It must be remembered that the measurements of CT with enhanced depth imaging optical coherence tomography (EDI-OCT) technology provide only an indirect index of the consequence of blood flow regulation in a vascular bed, yet cannot measure blood flow, volume, or velocity there. We, therefore, suggest that the EDI-OCT may be used to evaluate the issue of blood flow regulation. Furthermore, it has been reported that the body temperature of older persons is lower than that of younger people and that their tolerance of thermal changes is more limited.[8] So that, studies are required to evaluation the changes in CT during egzersize in older and young peoples.

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  8 in total

1.  Temperature modulating action of choroidal blood flow.

Authors:  L M Parver
Journal:  Eye (Lond)       Date:  1991       Impact factor: 3.775

2.  Physical exercise-induced changes in the core body temperature of mice depend more on ambient temperature than on exercise protocol or intensity.

Authors:  Samuel Penna Wanner; Kátia Anunciação Costa; Anne Danieli Nascimento Soares; Valbert Nascimento Cardoso; Cândido Celso Coimbra
Journal:  Int J Biometeorol       Date:  2013-07-16       Impact factor: 3.787

3.  Active defence of retinal temperature during hypothermia of the eye in cats.

Authors:  W L Stiehl; F González-Lima; A Carrera; L M Cuebas; R E Díaz
Journal:  J Physiol (Paris)       Date:  1986

4.  Choroidal blood flow. III. Reflexive control in human eyes.

Authors:  L M Parver; C R Auker; D O Carpenter
Journal:  Arch Ophthalmol       Date:  1983-10

5.  Choroidal blood flow as a heat dissipating mechanism in the macula.

Authors:  L M Parver; C Auker; D O Carpenter
Journal:  Am J Ophthalmol       Date:  1980-05       Impact factor: 5.258

Review 6.  Age-dependent changes in temperature regulation - a mini review.

Authors:  Clark M Blatteis
Journal:  Gerontology       Date:  2011-11-11       Impact factor: 5.140

Review 7.  The multifunctional choroid.

Authors:  Debora L Nickla; Josh Wallman
Journal:  Prog Retin Eye Res       Date:  2009-12-29       Impact factor: 21.198

8.  Choroidal thickness changes after dynamic exercise as measured by spectral-domain optical coherence tomography.

Authors:  Nihat Sayin; Necip Kara; Gokhan Pekel; Hasan Altinkaynak
Journal:  Indian J Ophthalmol       Date:  2015-05       Impact factor: 1.848

  8 in total

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