Literature DB >> 26860311

Lithium in Medicine: Mechanisms of Action.

Duarte Mota de Freitas1, Brian D Leverson2, Jesse L Goossens3.   

Abstract

In this chapter, we review the mechanism of action of lithium salts from a chemical perspective. A description on how lithium salts are used to treat mental illnesses, in particular bipolar disorder, and other disease states is provided. Emphasis is not placed on the genetics and the psychopharmacology of the ailments for which lithium salts have proven to be beneficial. Rather we highlight the application of chemical methodologies for the characterization of the cellular targets of lithium salts and their distribution in tissues.

Entities:  

Keywords:  Bipolar disorder; Glycogen synthase kinase-3β; Lithium; Mechanisms of action

Mesh:

Substances:

Year:  2016        PMID: 26860311     DOI: 10.1007/978-3-319-21756-7_15

Source DB:  PubMed          Journal:  Met Ions Life Sci        ISSN: 1559-0836


  4 in total

Review 1.  Pharmacological Approaches to Decelerate Aging: A Promising Path.

Authors:  Bahareh Hassani; Ghazal Goshtasbi; Shirin Nooraddini; Negar Firouzabadi
Journal:  Oxid Med Cell Longev       Date:  2022-07-11       Impact factor: 7.310

2.  In Vitro Human Umbilical Vein Endothelial Cells Response to Ionic Dissolution Products from Lithium-Containing 45S5 Bioactive Glass.

Authors:  Luis A Haro Durand; Gabriela E Vargas; Rosa Vera-Mesones; Alberto Baldi; María P Zago; María A Fanovich; Aldo R Boccaccini; Alejandro Gorustovich
Journal:  Materials (Basel)       Date:  2017-07-03       Impact factor: 3.623

3.  Quantification of lithium at ppm level in geological samples using nuclear reaction analysis.

Authors:  Nathaly De La Rosa; Per Kristiansson; E J Charlotta Nilsson; Linus Ros; Jan Pallon; Henrik Skogby
Journal:  J Radioanal Nucl Chem       Date:  2018-05-28       Impact factor: 1.371

Review 4.  The Role of Lithium in Management of Endocrine Tumors-A Comprehensive Review.

Authors:  Shilpa Thakur; Andrew Tobey; Joanna Klubo-Gwiezdzinska
Journal:  Front Oncol       Date:  2019-10-18       Impact factor: 6.244

  4 in total

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