| Literature DB >> 26860311 |
Duarte Mota de Freitas1, Brian D Leverson2, Jesse L Goossens3.
Abstract
In this chapter, we review the mechanism of action of lithium salts from a chemical perspective. A description on how lithium salts are used to treat mental illnesses, in particular bipolar disorder, and other disease states is provided. Emphasis is not placed on the genetics and the psychopharmacology of the ailments for which lithium salts have proven to be beneficial. Rather we highlight the application of chemical methodologies for the characterization of the cellular targets of lithium salts and their distribution in tissues.Entities:
Keywords: Bipolar disorder; Glycogen synthase kinase-3β; Lithium; Mechanisms of action
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Year: 2016 PMID: 26860311 DOI: 10.1007/978-3-319-21756-7_15
Source DB: PubMed Journal: Met Ions Life Sci ISSN: 1559-0836