Literature DB >> 26860105

Survivorship and clinical outcomes of 147 consecutive isolated or combined arthroscopic bone plug free meniscal allograft transplantation.

Stefano Zaffagnini1, Alberto Grassi2, Giulio Maria Marcheggiani Muccioli1, Andrea Benzi1, Margherita Serra1, Marco Rotini1, Laura Bragonzoni1, Maurilio Marcacci1.   

Abstract

PURPOSE: To present the results of a survival analysis of a series of 147 arthroscopic MAT procedures.
METHODS: One-hundred and forty-seven patients (117 males and 30 females) underwent arthroscopic MAT without bone plugs (82 medial MAT and 65 lateral MAT) using fresh-frozen, non-irradiated grafts. They were retrospectively reviewed at a mean of 4.0 ± 1.9-year follow-up. Mean age at surgery was 40.9 ± 11.2 (range 16.7-68.8) years; 70 patients (48 %) underwent combined procedures. Clinical evaluation was performed with KOOS, Lysholm and a 0-100 VAS for pain. Survival analysis was performed using two endpoints: surgical failure (revision procedure with direct relation to MAT) and clinical failure (revision procedure or poor Lysholm score, <65).
RESULTS: There was a significant (p < 0.05) and clinically relevant decrease in the VAS and increase in KOOS and Lysholm from pre-operative mean score to post-operative mean score. Seven (5 %) patients (two medial and five lateral) experienced surgical failure (five meniscectomies, one lateral graft peripheral suture and one unicompartmental knee arthroplasty). The mean overall survival time was 9.7 years (CI 9.1-10.3). As 16 (11 %) patients presented poor Lysholm score, a total of 23 (16 %) patients were considered clinical failures. The mean overall survival time was 8 years (CI 7.1-8.8). No statistically significant differences in failure and survival rate were present between medial and lateral MAT, isolated or combined MAT, patients >50 or <50 years old and patients with body mass index <25 or >25.
CONCLUSIONS: MAT, eventually associated with other needed procedures, was able to significantly relieve pain and improve function of the knee joint at midterm follow-up, with a survival rate from 9.7 to 8.0 years based on failure criteria. Most additional procedures were done in the first 2 post-operative years. MAT eventually associated with other needed procedures could represent an effective treatment for post-meniscectomy syndrome. LEVEL OF EVIDENCE: Therapeutic study, retrospective case series, Level IV.

Entities:  

Keywords:  Allograft; Arthroscopy; Biology; Knee; Meniscus; Replacement; Transplantation

Mesh:

Year:  2016        PMID: 26860105     DOI: 10.1007/s00167-016-4035-z

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  27 in total

1.  Arthroscopically assisted meniscal allograft transplantation in the knee: a medium-term subjective, clinical, and radiographical outcome evaluation.

Authors:  Bart Vundelinckx; Johan Bellemans; Johan Vanlauwe
Journal:  Am J Sports Med       Date:  2010-08-19       Impact factor: 6.202

2.  Long-term Subjective, Clinical, and Radiographic Outcome Evaluation of Meniscal Allograft Transplantation in the Knee.

Authors:  Bart Vundelinckx; Johan Vanlauwe; Johan Bellemans
Journal:  Am J Sports Med       Date:  2014-04-23       Impact factor: 6.202

3.  Comparative study on immediate versus delayed meniscus allograft transplantation: 4- to 6-year follow-up.

Authors:  Dong Jiang; Ying-Fang Ao; Xi Gong; Yong-Jian Wang; Zhuo-Zhao Zheng; Jia-Kuo Yu
Journal:  Am J Sports Med       Date:  2014-07-28       Impact factor: 6.202

4.  The role of the meniscus in the anterior-posterior stability of the loaded anterior cruciate-deficient knee. Effects of partial versus total excision.

Authors:  S C Shoemaker; K L Markolf
Journal:  J Bone Joint Surg Am       Date:  1986-01       Impact factor: 5.284

Review 5.  Meniscal allograft transplantation: how should we be doing it? A systematic review.

Authors:  Peter Myers; Francois Tudor
Journal:  Arthroscopy       Date:  2015-01-14       Impact factor: 4.772

6.  Combined osteochondral allograft and meniscal allograft transplantation: a survivorship analysis.

Authors:  Alan Getgood; Jonathon Gelber; Simon Gortz; Alison De Young; William Bugbee
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-02-12       Impact factor: 4.342

7.  Successful treatment of painful irreparable partial meniscal defects with a polyurethane scaffold: two-year safety and clinical outcomes.

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8.  Meniscus allograft transplantation: a comparison of medial and lateral procedures.

Authors:  Kyoung Ho Yoon; Sang Hak Lee; Soo Yeon Park; Hwan Jin Kim; Kee Yun Chung
Journal:  Am J Sports Med       Date:  2013-11-08       Impact factor: 6.202

9.  Meniscal allograft transplantation: long-term clinical results with radiological and magnetic resonance imaging correlations.

Authors:  Peter C M Verdonk; Koenraad L Verstraete; Karl F Almqvist; Kristof De Cuyper; Eric M Veys; Gust Verbruggen; René Verdonk
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2006-02-07       Impact factor: 4.342

Review 10.  The Knee injury and Osteoarthritis Outcome Score (KOOS): from joint injury to osteoarthritis.

Authors:  Ewa M Roos; L Stefan Lohmander
Journal:  Health Qual Life Outcomes       Date:  2003-11-03       Impact factor: 3.186

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  15 in total

Review 1.  Low-impact sports activities are feasible after meniscus transplantation: a systematic review.

Authors:  Sue D Barber-Westin; Frank R Noyes
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-07-27       Impact factor: 4.342

2.  Concomitant Arthroscopic Meniscal Allograft Transplantation and Anterior Cruciate Ligament Reconstruction.

Authors:  Bryan M Saltzman; Justin W Griffin; Nathan Wetters; Maximilian A Meyer; Brian J Cole; Adam B Yanke
Journal:  Arthrosc Tech       Date:  2016-10-11

3.  High-grade preoperative osteoarthritis of the index compartment is a major predictor of meniscal allograft failure.

Authors:  Philipp W Winkler; Nyaluma N Wagala; Jonathan D Hughes; Volker Musahl
Journal:  Arch Orthop Trauma Surg       Date:  2022-01-05       Impact factor: 3.067

4.  Clinical Replacement Strategies for Meniscus Tissue Deficiency.

Authors:  Dean Wang; Erik Gonzalez-Leon; Scott A Rodeo; Kyriacos A Athanasiou
Journal:  Cartilage       Date:  2021-11-20       Impact factor: 3.117

5.  Meniscal allograft transplantation: a meta-analysis.

Authors:  Manolito De Bruycker; Peter C M Verdonk; René C Verdonk
Journal:  SICOT J       Date:  2017-04-21

6.  Should the meniscal height be considered for preoperative sizing in meniscal transplantation?

Authors:  Alfredo Dos Santos Netto; Camila Cohen Kaleka; Mariana Kei Toma; Julio Cesar de Almeida E Silva; Ricardo de Paula Leite Cury; Patricia Maria de Moraes Barros Fucs; Nilson Roberto Severino
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-02-23       Impact factor: 4.342

7.  The results of meniscal allograft transplantation surgery: what is success?

Authors:  Henry Searle; Vipin Asopa; Simon Coleman; Ian McDermott
Journal:  BMC Musculoskelet Disord       Date:  2020-03-12       Impact factor: 2.362

8.  The potential of using semitendinosus tendon as autograft in rabbit meniscus reconstruction.

Authors:  Chenxi Li; Xiaoqing Hu; Qingyang Meng; Xin Zhang; Jingxian Zhu; Linghui Dai; Jin Cheng; Mingjin Zhong; Weili Shi; Bo Ren; Jiying Zhang; Xin Fu; Xiaoning Duan; Yingfang Ao
Journal:  Sci Rep       Date:  2017-08-01       Impact factor: 4.379

9.  Establishing Clinically Significant Outcomes After Meniscal Allograft Transplantation.

Authors:  Joseph N Liu; Anirudh K Gowd; Michael L Redondo; David R Christian; Brandon C Cabarcas; Adam B Yanke; Brian J Cole
Journal:  Orthop J Sports Med       Date:  2019-01-04

10.  Three-dimensional meniscus allograft sizing-a study of 280 healthy menisci.

Authors:  Silvan Beeler; Lukas Jud; Marco von Atzigen; Reto Sutter; Philipp Fürnstahl; Sandro F Fucentese; Lazaros Vlachopoulos
Journal:  J Orthop Surg Res       Date:  2020-02-24       Impact factor: 2.359

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