Literature DB >> 26859995

[Early Stages of Parkinson's Disease: Comparative Characteristics of Sleep-Wakefulness Cycle in Patients and Model Animals].

V M Kovalzon, M V Ugrumov, T S Pronina, V B Dorokhov, A I Manolov, V V Dolgikh, Y V Ukraintseva, L S Moiseenko, M G Poluektov, A L Kalinkin.   

Abstract

The results of study of sleep-wakefulness cycle in experimental models of pre-clinical and early clinical stages of Parkinson's disease present and compared to some clinical examples. The conclusion is, the increase in activity level and decrease in total amount of slow wave and paradoxical sleep in model animals are taking place at the same circadian period of the secretion of pineal melatonin as sleep disorders in patients.

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Year:  2015        PMID: 26859995

Source DB:  PubMed          Journal:  Fiziol Cheloveka        ISSN: 0131-1646


  2 in total

1.  Downregulation of CDK5 signaling in the dorsal striatum alters striatal microcircuits implicating the association of pathologies with circadian behavior in mice.

Authors:  Hu Zhou; Jingxin Zhang; Huaxiang Shi; Pengfei Li; Xin Sui; Yongan Wang; Liyun Wang
Journal:  Mol Brain       Date:  2022-06-14       Impact factor: 4.399

2.  Effects of striatal transplantation of cells transfected with GDNF gene without pre- and pro-regions in mouse model of Parkinson's disease.

Authors:  A Revishchin; L Moiseenko; N Kust; N Bazhenova; P Teslia; D Panteleev; V Kovalzon; G Pavlova
Journal:  BMC Neurosci       Date:  2016-06-10       Impact factor: 3.288

  2 in total

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