Fall of the Optical Wall: Freedom from the Tyranny of the Microscope Improves Glioma Risk Stratification.

A recent study uses an integrated genomic approach to identify biologically defined subgroups of adult diffuse glioma. These results further lay the foundation for a pathological classification scheme for gliomas that incorporates both histology and molecular biomarkers, which appears far more robust than the current scheme, based solely on morphology.