Literature DB >> 26859449

miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells.

Simon Raffel1, Andreas Trumpp2.   

Abstract

Leukemic stem cells (LSCs) are resistant to conventional chemotherapy and promote acute myeloid leukemia (AML) progression and recurrence. In this issue of Cancer Cell, Lechman and colleagues (2016) identify the microRNA miR-126 as a regulator of PI3K-AKT-mTOR and CDK3 signaling driving LSC self-renewal and chemotherapy resistance.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 26859449     DOI： 10.1016/j.ccell.2016.01.007

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  9 in total

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2.  MicroRNA-509-3p inhibits cell proliferation and invasion via downregulation of X-linked inhibitor of apoptosis in glioma.

Authors:  Peng Du; Xinping Luan; Yiwei Liao; Yiti Mu; Yang Yuan; Jingxuan Xu; Jingjing Zhang
Journal:  Oncol Lett       Date:  2017-11-10       Impact factor: 2.967

3.  miR-1204 targets VDR to promotes epithelial-mesenchymal transition and metastasis in breast cancer.

Authors:  Xiaoyan Liu; Lei Bi; Qin Wang; Mingxin Wen; Ce Li; Yidan Ren; Qinlian Jiao; Jian-Hua Mao; Chuanxin Wang; Guangwei Wei; Yunshan Wang
Journal:  Oncogene       Date:  2018-03-20       Impact factor: 9.867

Review 4.  miRNAs in acute myeloid leukemia.

Authors:  Qiong Liao; Bingping Wang; Xia Li; Guosheng Jiang
Journal:  Oncotarget       Date:  2017-01-10

5.  Upregulation of miR-99a is associated with poor prognosis of acute myeloid leukemia and promotes myeloid leukemia cell expansion.

Authors:  Xiaohui Si; Xiaoyun Zhang; Xing Hao; Yunan Li; Zizhen Chen; Yahui Ding; Hui Shi; Jie Bai; Yingdai Gao; Tao Cheng; Feng-Chun Yang; Yuan Zhou
Journal:  Oncotarget       Date:  2016-11-22

6.  Identification of differentially expressed miRNAs associated with thermal injury in epidermal stem cells based on RNA-sequencing.

Authors:  Hao-Tian Rong; De-Wu Liu
Journal:  Exp Ther Med       Date:  2020-01-14       Impact factor: 2.447

7.  Expression and prognosis analysis of DNMT family in acute myeloid leukemia.

Authors:  Ting-Juan Zhang; Liu-Chao Zhang; Zi-Jun Xu; Jing-Dong Zhou
Journal:  Aging (Albany NY)       Date:  2020-06-26       Impact factor: 5.682

8.  MiR-362-5p as a novel prognostic predictor of cytogenetically normal acute myeloid leukemia.

Authors:  Qiu-Ling Ma; Jing-Han Wang; Min Yang; Huan-Ping Wang; Jie Jin
Journal:  J Transl Med       Date:  2018-03-14       Impact factor: 5.531

Review 9.  Role of PI3K/AKT pathway in cancer: the framework of malignant behavior.

Authors:  Ningni Jiang; Qijie Dai; Xiaorui Su; Jianjiang Fu; Xuancheng Feng; Juan Peng
Journal:  Mol Biol Rep       Date:  2020-04-24       Impact factor: 2.742
  9 in total

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