Literature DB >> 26857708

Current Trends in the Oncologic and Surgical Managements of Breast Cancer in Women with Implants: Incidence, Diagnosis, and Treatment.

Paolo Veronesi1, Francesca De Lorenzi2, Pietro Loschi3, Mario Rietjens3, Umberto Veronesi1.   

Abstract

UNLABELLED: Breast augmentation is the most common cosmetic surgery in the United States, and thousands of augmented patients develop breast cancer each year. The possible effects of implants on cancer incidence, diagnosis, and treatment usually generate a disarming confusion. The present paper represents an update of the more recent oncologic and surgical strategies, aiming to support plastic and general surgeons in such challenging aspects. Several aspects of breast cancer management in augmented women are investigated, including (1) risk estimation and cancer characteristics, stage at diagnosis, and prognosis; (2) cancer diagnosis with clinical examination, mammography, ultrasound, and magnetic resonance imaging; (3) cancer treatment including breast conservation, intraoperative radiotherapy, sentinel node biopsy and mastectomy, and reconstruction. A brief resume of recommendations and conclusions is suggested, elucidating correct trends in the oncologic management of augmented patients and refusing well-established misconceptions: (1) breast augmentation does not increase the risk of breast cancer incidence, and it does not influence the prognosis; (2) possible risks exist in cancer detection due to technical difficulties; (3) sentinel lymph node detection is feasible; (4) intraoperative radiotherapy represents a good chance for conserving treatment; (5) immediate reconstruction with submuscular-subfascial implants is the most common procedure after mastectomy, and biological substitutes could support this procedure. Breast clinicians should be alerted because of high expectations of this subgroup of patients, accustomed to emphasize the aesthetic result. LEVEL OF EVIDENCE V: This journal requires that the authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Entities:  

Keywords:  Breast augmentation; Breast cancer; Implants and cancer; Intraoperative radiotherapy; Women with implant

Mesh:

Year:  2016        PMID: 26857708     DOI: 10.1007/s00266-016-0612-2

Source DB:  PubMed          Journal:  Aesthetic Plast Surg        ISSN: 0364-216X            Impact factor:   2.326


  3 in total

1.  A Novel Method of Implant Coverage for Post-Mastectomy Reconstruction after Previous Augmentation: A Case Report.

Authors:  Elisabetta Maria Cristina Rossi; Alessandra Invento; Marco Iera; Virgilio Sacchini; Paolo Veronesi; Francesca De Lorenzi
Journal:  Breast Care (Basel)       Date:  2020-01-28       Impact factor: 2.860

2.  Skin-reducing mastectomy and direct-to-implant reconstruction in giant phyllodes tumour of breast: case report.

Authors:  Francesco Ciancio; Alessandro Innocenti; Luigi Cagiano; Aurelio Portincasa; Domenico Parisi
Journal:  Int J Surg Case Rep       Date:  2017-11-13

Review 3.  Osteoprotegerin rich tumor microenvironment: implications in breast cancer.

Authors:  Sudeshna Goswami; Neelam Sharma-Walia
Journal:  Oncotarget       Date:  2016-07-05
  3 in total

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