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Literature DB >> 26856822

XRF-measured bone lead (Pb) as a biomarker for Pb exposure and toxicity among children diagnosed with Pb poisoning.

Aaron J Specht¹, Yanfen Lin², Marc Weisskopf³, Chonghuai Yan², Howard Hu⁴, Jian Xu², Linda H Nie¹.

Abstract

Childhood lead (Pb) poisoning remains a global issue, especially in industrial areas. In this study, 115 children with average age 5.7 years were recruited as either patient diagnosed with Pb poisoning or controls at Xinhua Hospital in China. The subjects' bone Pb was measured with a K-shell X-ray fluorescence (KXRF) and a portable X-ray fluorescence (XRF) system. A significant correlation between KXRF bone Pb and blood Pb and portable XRF and KXRF measurements were observed. The half-life of blood-lead was calculated to be 9.96 ± 3.92 d. Our results indicate that bone is a useful biomarker for Pb in children.

Entities: Chemical Disease Species

Keywords: In vivo; X-ray fluorescence; portable

Mesh：

Substances：
Biomarkers
Lead

Year: 2016 PMID： 26856822 PMCID： PMC4964874 DOI： 10.3109/1354750X.2016.1139183

Source DB: PubMed Journal: Biomarkers ISSN： 1354-750X Impact factor: 2.658

24 in total

1. Estimation and prediction of blood volume in infants and children.

Authors: O Linderkamp; H T Versmold; K P Riegel; K Betke
Journal: Eur J Pediatr Date: 1977-08-12 Impact factor: 3.183

2. A comparison of concentrations of lead in human tissues.

Authors: P S Barry
Journal: Br J Ind Med Date: 1975-05

Review 3. Basic anatomical and physiological data for use in radiological protection: the skeleton. A report of a Task Group of Committee 2 of the International Commission on Radiological Protection.

Authors:
Journal: Ann ICRP Date: 1995

4. In vivo measurements of bone lead--a comparison of two x-ray fluorescence techniques used at three different bone sites.

Authors: L J Somervaille; U Nilsson; D R Chettle; I Tell; M C Scott; A Schütz; S Mattsson; S Skerfving
Journal: Phys Med Biol Date: 1989-12 Impact factor: 3.609

5. The uptake and excretion of lead by young children.

Authors: M J Duggan
Journal: Arch Environ Health Date: 1983 Jul-Aug

6. Blood lead levels and cumulative blood lead index (CBLI) as predictors of late neurodevelopment in lead poisoned children.

Authors: Linda H Nie; Robert O Wright; David C Bellinger; Javed Hussain; Chitra Amarasiriwardena; David R Chettle; Ana Pejović-Milić; Alan Woolf; Michael Shannon
Journal: Biomarkers Date: 2011-08-09 Impact factor: 2.658

7. Blood lead level and kidney function in US adolescents: The Third National Health and Nutrition Examination Survey.

Authors: Jeffrey J Fadrowski; Ana Navas-Acien; Maria Tellez-Plaza; Eliseo Guallar; Virginia M Weaver; Susan L Furth
Journal: Arch Intern Med Date: 2010-01-11

8. Accumulated body burden and endogenous release of lead in employees of a lead smelter.

Authors: D E Fleming; D Boulay; N S Richard; J P Robin; C L Gordon; C E Webber; D R Chettle
Journal: Environ Health Perspect Date: 1997-02 Impact factor: 9.031

9. Low-level environmental lead exposure and children's intellectual function: an international pooled analysis.

Authors: Bruce P Lanphear; Richard Hornung; Jane Khoury; Kimberly Yolton; Peter Baghurst; David C Bellinger; Richard L Canfield; Kim N Dietrich; Robert Bornschein; Tom Greene; Stephen J Rothenberg; Herbert L Needleman; Lourdes Schnaas; Gail Wasserman; Joseph Graziano; Russell Roberts
Journal: Environ Health Perspect Date: 2005-07 Impact factor: 9.031

10. Calculating bone-lead measurement variance.

Authors: A C Todd
Journal: Environ Health Perspect Date: 2000-05 Impact factor: 9.031

16 in total

1. Measurements of Strontium Levels in Human Bone In Vivo Using Portable X-ray Fluorescence (XRF).

Authors: Aaron J Specht; Farshad Mostafaei; Yanfen Lin; Jian Xu; Linda H Nie
Journal: Appl Spectrosc Date: 2017-03-02 Impact factor: 2.388

2. Validation of x-ray fluorescence measurements of metals in toenail clippings against inductively coupled plasma mass spectrometry in a Nigerian population.

Authors: Aaron J Specht; Kale Kponee; Kpobari W Nkpaa; Prentiss H Balcom; Jennifer Weuve; Linda H Nie; Marc G Weisskopf
Journal: Physiol Meas Date: 2018-08-31 Impact factor: 2.833

10. A novel calibration for L-shell x-ray fluorescence measurements of bone lead concentration using the strontium Kβ/Kαratio.

Authors: Mihai R Gherase; Blaz Serna; Sarah Kroeker
Journal: Physiol Meas Date: 2021-05-14 Impact factor: 2.833

XRF-measured bone lead (Pb) as a biomarker for Pb exposure and toxicity among children diagnosed with Pb poisoning.

1. Estimation and prediction of blood volume in infants and children.

2. A comparison of concentrations of lead in human tissues.

Review 3. Basic anatomical and physiological data for use in radiological protection: the skeleton. A report of a Task Group of Committee 2 of the International Commission on Radiological Protection.

4. In vivo measurements of bone lead--a comparison of two x-ray fluorescence techniques used at three different bone sites.

5. The uptake and excretion of lead by young children.

6. Blood lead levels and cumulative blood lead index (CBLI) as predictors of late neurodevelopment in lead poisoned children.

7. Blood lead level and kidney function in US adolescents: The Third National Health and Nutrition Examination Survey.

8. Accumulated body burden and endogenous release of lead in employees of a lead smelter.

9. Low-level environmental lead exposure and children's intellectual function: an international pooled analysis.

10. Calculating bone-lead measurement variance.

1. Measurements of Strontium Levels in Human Bone In Vivo Using Portable X-ray Fluorescence (XRF).

2. Validation of x-ray fluorescence measurements of metals in toenail clippings against inductively coupled plasma mass spectrometry in a Nigerian population<sup/>.

3. Lead exposure biomarkers in the Common Loon.

4. Comparison of bone lead measured via portable x-ray fluorescence across and within bones.

5. Theoretical modeling of a portable x-ray tube based KXRF system to measure lead in bone.

6. Susceptibility to Environmental Heavy Metal Toxicity among Americans with Kidney Disease.

7. Quantification of manganese and mercury in toenail in vivo using portable X-ray fluorescence (XRF).

8. Feasibility of a portable X-ray fluorescence device for bone lead measurements of condor bones.

9. Blood lead, bone lead and child attention-deficit-hyperactivity-disorder-like behavior.

10. A novel calibration for L-shell x-ray fluorescence measurements of bone lead concentration using the strontium Kβ/Kαratio.