Literature DB >> 26855503

Current Role of Genetics in Hematologic Malignancies.

Gaurav Prakash1, Anupriya Kaur2, Pankaj Malhotra1, Alka Khadwal1, Prashant Sharma3, Vikas Suri1, Neelam Varma3, Subhash Varma1.   

Abstract

Rapidly changing field of genetic technology and its application in the management of hematological malignancies has brought significant improvement in treatment and outcome of these disorders. Today, genetics plays pivotal role in diagnosis and prognostication of most hematologic neoplasms. The utilization of genetic tests in deciding specific treatment of various hematologic malignancies as well as for evaluation of depth of treatment response is rapidly advancing. Therefore, it is imperative for practitioners working in the field of hemato-oncology to have sufficient understanding of the basic concepts of genetics in order to comprehend upcoming molecular research in this area and to translate the same for patient care.

Entities:  

Keywords:  Genetics; Hematology; Molecular tests; Oncology

Year:  2015        PMID： 26855503      PMCID： PMC4733682          DOI： 10.1007/s12288-015-0584-4

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN： 0971-4502            Impact factor:   0.900


  46 in total

1.  The discovery of the human chromosome number in Lund, 1955-1956.

Authors:  Peter S Harper
Journal:  Hum Genet       Date:  2006-03       Impact factor: 4.132

2.  Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia.

Authors:  Alessandra Ferrajoli; Tait D Shanafelt; Cristina Ivan; Masayoshi Shimizu; Kari G Rabe; Nazila Nouraee; Mariko Ikuo; Asish K Ghosh; Susan Lerner; Laura Z Rassenti; Lianchun Xiao; Jianhua Hu; James M Reuben; Steliana Calin; M James You; John T Manning; William G Wierda; Zeev Estrov; Susan O'Brien; Thomas J Kipps; Michael J Keating; Neil E Kay; George A Calin
Journal:  Blood       Date:  2013-07-02       Impact factor: 22.113

Review 3.  Chronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatment.

Authors:  Michael Hallek
Journal:  Am J Hematol       Date:  2015-05       Impact factor: 10.047

4.  Phase I/II study of combination therapy with sorafenib, idarubicin, and cytarabine in younger patients with acute myeloid leukemia.

Authors:  Farhad Ravandi; Jorge E Cortes; Daniel Jones; Stefan Faderl; Guillermo Garcia-Manero; Marina Y Konopleva; Susan O'Brien; Zeev Estrov; Gautam Borthakur; Deborah Thomas; Sherry R Pierce; Mark Brandt; Anna Byrd; B Nebiyou Bekele; Keith Pratz; Rajyalakshmi Luthra; Mark Levis; Michael Andreeff; Hagop M Kantarjian
Journal:  J Clin Oncol       Date:  2010-03-08       Impact factor: 44.544

Review 5.  Standardized definitions of molecular response in chronic myeloid leukemia.

Authors:  N C P Cross; H E White; M C Müller; G Saglio; A Hochhaus
Journal:  Leukemia       Date:  2012-04-16       Impact factor: 11.528

6.  Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a Cancer and Leukemia Group B Study.

Authors:  Peter Paschka; Guido Marcucci; Amy S Ruppert; Krzysztof Mrózek; Hankui Chen; Rick A Kittles; Tamara Vukosavljevic; Danilo Perrotti; James W Vardiman; Andrew J Carroll; Jonathan E Kolitz; Richard A Larson; Clara D Bloomfield
Journal:  J Clin Oncol       Date:  2006-08-20       Impact factor: 44.544

7.  Wilms tumor 1 gene mutations are associated with a higher risk of recurrence in young adults with acute myeloid leukemia: a study from the Acute Leukemia French Association.

Authors:  Aline Renneville; Nicolas Boissel; Virginie Zurawski; Laura Llopis; Valéria Biggio; Olivier Nibourel; Nathalie Philippe; Xavier Thomas; Hervé Dombret; Claude Preudhomme
Journal:  Cancer       Date:  2009-08-15       Impact factor: 6.860

8.  Evaluating cell-of-origin subtype methods for predicting diffuse large B-cell lymphoma survival: a meta-analysis of gene expression profiling and immunohistochemistry algorithms.

Authors:  Jay A Read; Jean L Koff; Loretta J Nastoupil; Jessica N Williams; Jonathon B Cohen; Christopher R Flowers
Journal:  Clin Lymphoma Myeloma Leuk       Date:  2014-06-12

Review 9.  The critical role of chromosome translocations in human leukemias.

Authors:  J D Rowley
Journal:  Annu Rev Genet       Date:  1998       Impact factor: 16.830

Review 10.  Viral diagnostics in the era of digital polymerase chain reaction.

Authors:  Ruth Hall Sedlak; Keith R Jerome
Journal:  Diagn Microbiol Infect Dis       Date:  2012-11-20       Impact factor: 2.803
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  3 in total

1.  Old and New Prognostic Markers in Pediatric ALL.

Authors:  Hara Prasad Pati; Prashant Sharma
Journal:  Indian J Hematol Blood Transfus       Date:  2016-02-23       Impact factor: 0.900

Review 2.  Abnormal microRNA expression in the course of hematological malignancies.

Authors:  Agnieszka Szymczyk; Arkadiusz Macheta; Monika Podhorecka
Journal:  Cancer Manag Res       Date:  2018-10-08       Impact factor: 3.989

Review 3.  The Role of N6-Methyladenosine (m6A) Methylation Modifications in Hematological Malignancies.

Authors:  Yan Zhao; Hongling Peng
Journal:  Cancers (Basel)       Date:  2022-01-11       Impact factor: 6.639
  3 in total

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