Literature DB >> 26855335

Stable mixed chimerism and tolerance to human organ transplants.

Samuel Strober1.   

Abstract

Tolerance to combined kidney and hematopoietic cell transplant has been achieved in humans after establishment of mixed chimerism allowing for the withdrawal of immunosuppressive drugs. The seminal contributions of Ray Owen provided the scientific basis for the human protocol.

Entities:  

Keywords:  human organ transplants; mixed chimerism; tolerance

Mesh：

Year:  2016        PMID： 26855335      PMCID： PMC5063066          DOI： 10.1080/19381956.2015.1115584

Source DB:  PubMed          Journal:  Chimerism        ISSN： 1938-1964


  44 in total

1.  Actively acquired tolerance of foreign cells.

Authors:  R E BILLINGHAM; L BRENT; P B MEDAWAR
Journal:  Nature       Date:  1953-10-03       Impact factor: 49.962

Review 2.  Bone-marrow transplantation (first of two parts).

Authors:  E Thomas; R Storb; R A Clift; A Fefer; F L Johnson; P E Neiman; K G Lerner; H Glucksberg; C D Buckner
Journal:  N Engl J Med       Date:  1975-04-17       Impact factor: 91.245

3.  Comparison of chimeric acid and non-chimeric tolerance using posttransplant total lymphoid irradiation: cytokine expression and chronic rejection.

Authors:  K Hayamizu; F Lan; P Huie; R K Sibley; S Strober
Journal:  Transplantation       Date:  1999-10-15       Impact factor: 4.939

4.  Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts.

Authors:  P L Weiden; N Flournoy; E D Thomas; R Prentice; A Fefer; C D Buckner; R Storb
Journal:  N Engl J Med       Date:  1979-05-10       Impact factor: 91.245

5.  Protective conditioning for acute graft-versus-host disease.

Authors:  Robert Lowsky; Tsuyoshi Takahashi; Yin Ping Liu; Sussan Dejbakhsh-Jones; F Carl Grumet; Judith A Shizuru; Ginna G Laport; Keith E Stockerl-Goldstein; Laura J Johnston; Richard T Hoppe; Daniel A Bloch; Karl G Blume; Robert S Negrin; Samuel Strober
Journal:  N Engl J Med       Date:  2005-09-29       Impact factor: 91.245

6.  Induced immune tolerance for kidney transplantation.

Authors:  John D Scandling; Stephan Busque; Judith A Shizuru; Edgar G Engleman; Samuel Strober
Journal:  N Engl J Med       Date:  2011-10-06       Impact factor: 91.245

7.  Survival of primates following orthotopic cardiac transplantation treated with total lymphoid irradiation and chemical immune suppression.

Authors:  J L Pennock; B A Reitz; C P Bieber; S Aziz; P E Oyer; S Strober; R Hoppe; H S Kaplan; E B Stinson; N E Shumway
Journal:  Transplantation       Date:  1981-12       Impact factor: 4.939

8.  Treatment of cadaveric renal transplant recipients with total lymphoid irradiation, antithymocyte globulin, and low-dose prednisone.

Authors:  B Levin; R T Hoppe; G Collins; E Miller; M Waer; C Bieber; T Girinsky; S Strober
Journal:  Lancet       Date:  1985-12-14       Impact factor: 79.321

9.  Clinical and immunological studies of cadaveric renal transplant recipients given total-lymphoid irradiation and maintained on low-dose prednisone.

Authors:  V Saper; D Chow; E D Engleman; R T Hoppe; B Levin; G Collins; S Strober
Journal:  Transplantation       Date:  1988-03       Impact factor: 4.939

10.  Host conditioning with total lymphoid irradiation and antithymocyte globulin prevents graft-versus-host disease: the role of CD1-reactive natural killer T cells.

Authors:  Fengshuo Lan; Defu Zeng; Masanori Higuchi; John P Higgins; Samuel Strober
Journal:  Biol Blood Marrow Transplant       Date:  2003-06       Impact factor: 5.742
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  2 in total

Review 1.  Role of exosomes in tumour and transplant immune regulation.

Authors:  Diego A Lema; William J Burlingham
Journal:  Scand J Immunol       Date:  2019-07-31       Impact factor: 3.487

Review 2.  Self-Centered Function of Adaptive Immunity in Regulation of Immune Responses and in Tolerance.

Authors:  Silvana Balzar
Journal:  J Immunol Res       Date:  2021-12-02       Impact factor: 4.818
  2 in total

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