Literature DB >> 2685474

Phenotyping of acute myelomonocytic (AMMOL) and monocytic leukemia (AMOL): association of T-cell-related antigens and skin-infiltration in AMOL.

M Schwonzen1, N Kuehn, B Vetten, V Diehl, M Pfreundschuh.   

Abstract

Leukemic blast cells in 25 cases of AMMOL (13 cases) and AMOL (12 cases) were positive for My7 (CD13) and My4 (CD14), while only 44% reacted with LeuM3 (another CD14 MoAb). T-cell-related antigens were detected in 44% of the cases (CD2, 24%; CD4, 12%; CD7 36%). The expression of LeuM3 and TcrAg on blast and monocytic cells was mutually exclusive, with three cases expressing neither LeuM3 nor TcrAg. All six patients with myeloperoxidase negative AMOL and the TcrAG+/LeuM3- phenotype had leukemic skin infiltrations.

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Year:  1989        PMID: 2685474     DOI: 10.1016/0145-2126(89)90042-8

Source DB:  PubMed          Journal:  Leuk Res        ISSN: 0145-2126            Impact factor:   3.156


  5 in total

1.  Lymphomas of true histiocytic origin. Expression of different phenotypes in so-called true histiocytic lymphoma and malignant histiocytosis.

Authors:  S M Hsu; Y S Ho; P L Hsu
Journal:  Am J Pathol       Date:  1991-06       Impact factor: 4.307

2.  Atypical presentation of acute myeloid leukemia: cardiac myeloid sarcoma.

Authors:  Fabio Rigamonti; P Beris; A Sanchez-Pareja; P Meyer; G Ashrafpoor; S Zaza; J Passweg; Y Chalandon
Journal:  Int J Hematol       Date:  2009-04-23       Impact factor: 2.490

3.  Monoclonal antibody FW6 generated against a mucin-carbohydrate of human amniotic fluid recognises a colonic tumour-associated epitope.

Authors:  M Schwonzen; R Schmits; S E Baldus; M Vierbuchen; F G Hanisch; M Pfreundschuh; V Diehl; J Bara; G Uhlenbruck
Journal:  Br J Cancer       Date:  1992-04       Impact factor: 7.640

Review 4.  Diagnostic challenges in acute monoblastic/monocytic leukemia in children.

Authors:  Elena Varotto; Eleonora Munaretto; Francesca Stefanachi; Fiammetta Della Torre; Barbara Buldini
Journal:  Front Pediatr       Date:  2022-09-28       Impact factor: 3.569

Review 5.  Leukaemia cutis as a specific skin involvement in chronic myelomonocytic leukaemia and review of the literature: Acknowledgments.

Authors:  Yanhong Qiao; Jinli Jian; Lijuan Deng; Hongjuan Tian; Bei Liu
Journal:  Transl Cancer Res       Date:  2020-08       Impact factor: 1.241

  5 in total

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