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Literature DB >> 26854642

Synthetic Prions Provide Clues for Understanding Prion Diseases.

Abstract

This Commentary highlights the article by Makarava et al that discusses the formation of synthetic prions and the role of substrate levels in their evolution.

Entities: Disease Species

Mesh：

Substances：
Prions

Year: 2016 PMID： 26854642 PMCID： PMC5808135 DOI： 10.1016/j.ajpath.2015.12.005

Source DB: PubMed Journal: Am J Pathol ISSN： 0002-9440 Impact factor: 4.307

21 in total

1. Parallel in-register intermolecular β-sheet architectures for prion-seeded prion protein (PrP) amyloids.

Authors: Bradley R Groveman; Michael A Dolan; Lara M Taubner; Allison Kraus; Reed B Wickner; Byron Caughey
Journal: J Biol Chem Date: 2014-07-15 Impact factor: 5.157

2. Biological evidence that scrapie agent has an independent genome.

Authors: M E Bruce; A G Dickinson
Journal: J Gen Virol Date: 1987-01 Impact factor: 3.891

3. Synthetic mammalian prions.

Authors: Giuseppe Legname; Ilia V Baskakov; Hoang-Oanh B Nguyen; Detlev Riesner; Fred E Cohen; Stephen J DeArmond; Stanley B Prusiner
Journal: Science Date: 2004-07-30 Impact factor: 47.728

4. Darwinian evolution of prions in cell culture.

Authors: Jiali Li; Shawn Browning; Sukhvir P Mahal; Anja M Oelschlegel; Charles Weissmann
Journal: Science Date: 2009-12-31 Impact factor: 47.728

Review 5. Prions.

Authors: S B Prusiner
Journal: Proc Natl Acad Sci U S A Date: 1998-11-10 Impact factor: 11.205

Synthetic Prions Provide Clues for Understanding Prion Diseases.

1. Parallel in-register intermolecular β-sheet architectures for prion-seeded prion protein (PrP) amyloids.

2. Biological evidence that scrapie agent has an independent genome.

3. Synthetic mammalian prions.

4. Darwinian evolution of prions in cell culture.

Review 5. Prions.

6. Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.

7. Genesis of mammalian prions: from non-infectious amyloid fibrils to a transmissible prion disease.

8. Recombinant prion protein induces a new transmissible prion disease in wild-type animals.

9. Protease-sensitive synthetic prions.

10. The structure of the infectious prion protein: experimental data and molecular models.

1. Novel strain properties distinguishing sporadic prion diseases sharing prion protein genotype and prion type.