Literature DB >> 26851184

DNA-Guided Precision Medicine for Cancer: A Case of Irrational Exuberance?

Emile E Voest1, Rene Bernards2.   

Abstract

Precision treatment with targeted cancer drugs requires the selection of patients who are most likely to benefit from a given therapy. We argue here that the use of a combination of both DNA and transcriptome analyses will significantly improve drug response prediction. ©2016 American Association for Cancer Research.

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Year:  2016        PMID： 26851184     DOI： 10.1158/2159-8290.CD-15-1321

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  15 in total

Review 1.  Implementing Genome-Driven Oncology.

Authors:  David M Hyman; Barry S Taylor; José Baselga
Journal:  Cell       Date:  2017-02-09       Impact factor: 41.582

2.  Risk and benefit for umbrella trials in oncology: a systematic review and meta-analysis.

Authors:  Karolina Strzebonska; Mateusz Blukacz; Mateusz T Wasylewski; Maciej Polak; Bishal Gyawali; Marcin Waligora
Journal:  BMC Med       Date:  2022-07-08       Impact factor: 11.150

Review 3.  Precision Oncology: The Road Ahead.

Authors:  Daniela Senft; Mark D M Leiserson; Eytan Ruppin; Ze'ev A Ronai
Journal:  Trends Mol Med       Date:  2017-09-05       Impact factor: 11.951

4.  MECP2 variation in Rett syndrome-An overview of current coverage of genetic and phenotype data within existing databases.

Authors:  Gillian S Townend; Friederike Ehrhart; Henk J van Kranen; Mark Wilkinson; Annika Jacobsen; Marco Roos; Egon L Willighagen; David van Enckevort; Chris T Evelo; Leopold M G Curfs
Journal:  Hum Mutat       Date:  2018-05-21       Impact factor: 4.878

5.  A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids.

Authors:  Nhan Phan; Jenny J Hong; Bobby Tofig; Matthew Mapua; David Elashoff; Neda A Moatamed; Jin Huang; Sanaz Memarzadeh; Robert Damoiseaux; Alice Soragni
Journal:  Commun Biol       Date:  2019-02-25

6.  Precision oncology: lessons learned and challenges for the future.

Authors:  Hsih-Te Yang; Ronak H Shah; David Tegay; Kenan Onel
Journal:  Cancer Manag Res       Date:  2019-08-07       Impact factor: 3.989

7.  Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.

Authors:  Georgios Vlachogiannis; Somaieh Hedayat; Alexandra Vatsiou; Yann Jamin; Javier Fernández-Mateos; Khurum Khan; Andrea Lampis; Katherine Eason; Ian Huntingford; Rosemary Burke; Mihaela Rata; Dow-Mu Koh; Nina Tunariu; David Collins; Sanna Hulkki-Wilson; Chanthirika Ragulan; Inmaculada Spiteri; Sing Yu Moorcraft; Ian Chau; Sheela Rao; David Watkins; Nicos Fotiadis; Maria Bali; Mahnaz Darvish-Damavandi; Hazel Lote; Zakaria Eltahir; Elizabeth C Smyth; Ruwaida Begum; Paul A Clarke; Jens C Hahne; Mitchell Dowsett; Johann de Bono; Paul Workman; Anguraj Sadanandam; Matteo Fassan; Owen J Sansom; Suzanne Eccles; Naureen Starling; Chiara Braconi; Andrea Sottoriva; Simon P Robinson; David Cunningham; Nicola Valeri
Journal:  Science       Date:  2018-02-23       Impact factor: 47.728

Review 8.  Precision Medicine Gains Momentum: Novel 3D Models and Stem Cell-Based Approaches in Head and Neck Cancer.

Authors:  Annette Affolter; Anne Lammert; Johann Kern; Claudia Scherl; Nicole Rotter
Journal:  Front Cell Dev Biol       Date:  2021-07-08

9.  Predicting clinical benefit from everolimus in patients with advanced solid tumors, the CPCT-03 study.

Authors:  Fleur Weeber; Geert A Cirkel; Marlous Hoogstraat; Sander Bins; Christa G M Gadellaa-van Hooijdonk; Salo Ooft; Erik van Werkhoven; Stefan M Willems; Marijn van Stralen; Wouter B Veldhuis; Nicolle J M Besselink; Hugo M Horlings; Neeltje Steeghs; Maja J de Jonge; Marlies H G Langenberg; Lodewyk F A Wessels; Edwin P J G Cuppen; J H Schellens; Stefan Sleijfer; Martijn P Lolkema; Emile E Voest
Journal:  Oncotarget       Date:  2017-03-08

10.  Somatic mutations in salivary duct carcinoma and potential therapeutic targets.

Authors:  Timothy K Khoo; Bing Yu; Jonathan R Clark; Ruta Gupta; Joel A Smith; Angus J Clarke; Peter P Luk; Christina I Selinger; Kate L Mahon; Spiridoula Kraitsek; Carsten Palme; Michael J Boyer; Marcel E Dinger; Mark J Cowley; Sandra A O'Toole
Journal:  Oncotarget       Date:  2017-05-25
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