Literature DB >> 26851182

Adenoid Cystic Carcinoma Can Be Driven by MYB or MYBL1 Rearrangements: New Insights into MYB and Tumor Biology.

Thomas J Gonda1, Robert G Ramsay2.   

Abstract

A majority of adenoid cystic carcinomas (AdCC)-rare tumors of the salivary gland and some other organs-have recently been found to be driven by chromosomal translocations resulting in MYB-NFIB fusions. Brayer and colleagues and Mitani and colleagues have now reported that AdCCs can alternatively be driven by similar rearrangements involving a second MYB family gene, MYBL1, and that these two drivers act in remarkably similar ways. ©2016 American Association for Cancer Research.

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Year:  2016        PMID： 26851182     DOI： 10.1158/2159-8290.CD-15-1470

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  14 in total

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Journal:  Am J Pathol       Date:  2017-07-20       Impact factor: 4.307

2.  A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.

Authors:  Russell J H Ryan; Jelena Petrovic; Dylan M Rausch; Yeqiao Zhou; Caleb A Lareau; Michael J Kluk; Amanda L Christie; Winston Y Lee; Daniel R Tarjan; Bingqian Guo; Laura K H Donohue; Shawn M Gillespie; Valentina Nardi; Ephraim P Hochberg; Stephen C Blacklow; David M Weinstock; Robert B Faryabi; Bradley E Bernstein; Jon C Aster; Warren S Pear
Journal:  Cell Rep       Date:  2017-10-17       Impact factor: 9.423

3.  Establishment of patient-derived xenograft models of adenoid cystic carcinoma to assess pre-clinical efficacy of combination therapy of a PI3K inhibitor and retinoic acid.

Authors:  Bao Sun; Yu Wang; Jingjing Sun; Chunye Zhang; Ronghui Xia; Shengming Xu; Shuyang Sun; Jiang Li
Journal:  Am J Cancer Res       Date:  2021-03-01       Impact factor: 6.166

4.  Genetic analysis of microglandular adenosis and acinic cell carcinomas of the breast provides evidence for the existence of a low-grade triple-negative breast neoplasia family.

Authors:  Felipe C Geyer; Samuel H Berman; Caterina Marchiò; Kathleen A Burke; Elena Guerini-Rocco; Salvatore Piscuoglio; Charlotte Ky Ng; Fresia Pareja; Hannah Y Wen; Zoltan Hodi; Stuart J Schnitt; Emad A Rakha; Ian O Ellis; Larry Norton; Britta Weigelt; Jorge S Reis-Filho
Journal:  Mod Pathol       Date:  2016-10-07       Impact factor: 7.842

5.  Identification of potential transcriptomic markers in developing pediatric sepsis: a weighted gene co-expression network analysis and a case-control validation study.

Authors:  Yiping Li; Yanhong Li; Zhenjiang Bai; Jian Pan; Jian Wang; Fang Fang
Journal:  J Transl Med       Date:  2017-12-13       Impact factor: 5.531

6.  Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast.

Authors:  Salvatore Piscuoglio; Charlotte K Y Ng; Felipe C Geyer; Kathleen A Burke; Catherine F Cowell; Luciano G Martelotto; Rachael Natrajan; Tatiana Popova; Christopher A Maher; Raymond S Lim; Ino de Bruijn; Odette Mariani; Larry Norton; Anne Vincent-Salomon; Britta Weigelt; Jorge S Reis-Filho
Journal:  NPJ Breast Cancer       Date:  2017-12-01

Review 7.  Triple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants.

Authors:  Fresia Pareja; Felipe C Geyer; Caterina Marchiò; Kathleen A Burke; Britta Weigelt; Jorge S Reis-Filho
Journal:  NPJ Breast Cancer       Date:  2016-11-16

8.  Personalized oncogenomic analysis of metastatic adenoid cystic carcinoma: using whole-genome sequencing to inform clinical decision-making.

Authors:  Manik Chahal; Erin Pleasance; Jasleen Grewal; Eric Zhao; Tony Ng; Erin Chapman; Martin R Jones; Yaoqing Shen; Karen L Mungall; Melika Bonakdar; Gregory A Taylor; Yussanne Ma; Andrew J Mungall; Richard A Moore; Howard Lim; Daniel Renouf; Stephen Yip; Steven J M Jones; Marco A Marra; Janessa Laskin
Journal:  Cold Spring Harb Mol Case Stud       Date:  2018-04-02

9.  Mut2Vec: distributed representation of cancerous mutations.

Authors:  Sunkyu Kim; Heewon Lee; Keonwoo Kim; Jaewoo Kang
Journal:  BMC Med Genomics       Date:  2018-04-20       Impact factor: 3.063

10.  The MYB/miR-130a/NDRG2 axis modulates tumor proliferation and metastatic potential in salivary adenoid cystic carcinoma.

Authors:  Yu Wang; Chun-Ye Zhang; Rong-Hui Xia; Jing Han; Bao Sun; Shu-Yang Sun; Jiang Li
Journal:  Cell Death Dis       Date:  2018-09-11       Impact factor: 8.469
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