Literature DB >> 26850162

Antimicrobial resistance dashboard application for mapping environmental occurrence and resistant pathogens.

Robert D Stedtfeld1, Maggie R Williams1, Umama Fakher1, Timothy A Johnson2, Tiffany M Stedtfeld1, Fang Wang3, Walid T Khalife4, Mary Hughes5, Brett E Etchebarne5, James M Tiedje6, Syed A Hashsham7.   

Abstract

An antibiotic resistance (AR) Dashboard application is being developed regarding the occurrence of antibiotic resistance genes (ARG) and bacteria (ARB) in environmental and clinical settings. The application gathers and geospatially maps AR studies, reported occurrence and antibiograms, which can be downloaded for offline analysis. With the integration of multiple data sets, the database can be used on a regional or global scale to identify hot spots for ARGs and ARB; track and link spread and transmission, quantify environmental or human factors influencing presence and persistence of ARG harboring organisms; differentiate natural ARGs from those distributed via human or animal activity; cluster and compare ARGs connections in different environments and hosts; and identify genes that can be used as proxies to routinely monitor anthropogenic pollution. To initially populate and develop the AR Dashboard, a qPCR ARG array was tested with 30 surface waters, primary influent from three waste water treatment facilities, ten clinical isolates from a regional hospital and data from previously published studies including river, park soil and swine farm samples. Interested users are invited to download a beta version (available on iOS or Android), submit AR information using the application, and provide feedback on current and prospective functionalities. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  AR dashboard database application; antibiotic resistance gene qPCR array; environmental resistome; mapping genes; mobile genetic elements

Mesh:

Substances:

Year:  2016        PMID: 26850162      PMCID: PMC5968356          DOI: 10.1093/femsec/fiw020

Source DB:  PubMed          Journal:  FEMS Microbiol Ecol        ISSN: 0168-6496            Impact factor:   4.194


  31 in total

Review 1.  Call of the wild: antibiotic resistance genes in natural environments.

Authors:  Heather K Allen; Justin Donato; Helena Huimi Wang; Karen A Cloud-Hansen; Julian Davies; Jo Handelsman
Journal:  Nat Rev Microbiol       Date:  2010-03-01       Impact factor: 60.633

Review 2.  Tackling antibiotic resistance: the environmental framework.

Authors:  Thomas U Berendonk; Célia M Manaia; Christophe Merlin; Despo Fatta-Kassinos; Eddie Cytryn; Fiona Walsh; Helmut Bürgmann; Henning Sørum; Madelaine Norström; Marie-Noëlle Pons; Norbert Kreuzinger; Pentti Huovinen; Stefania Stefani; Thomas Schwartz; Veljo Kisand; Fernando Baquero; José Luis Martinez
Journal:  Nat Rev Microbiol       Date:  2015-03-30       Impact factor: 60.633

3.  Prevalence of sulfonamide-resistant bacteria, resistance genes and integron-associated horizontal gene transfer in natural water bodies and soils adjacent to a swine feedlot in northern Taiwan.

Authors:  Jih-Tay Hsu; Chia-Yang Chen; Chu-Wen Young; Wei-Liang Chao; Mao-Hao Li; Yung-Hsin Liu; Chu-Ming Lin; Chingwen Ying
Journal:  J Hazard Mater       Date:  2014-03-03       Impact factor: 10.588

4.  Occurrence of antibiotics and antibiotic resistance genes in a sewage treatment plant and its effluent-receiving river.

Authors:  Jian Xu; Yan Xu; Hongmei Wang; Changsheng Guo; Huiyun Qiu; Yan He; Yuan Zhang; Xiaochen Li; Wei Meng
Journal:  Chemosphere       Date:  2014-03-12       Impact factor: 7.086

5.  Solving the Antibiotic Crisis.

Authors:  Gerard D Wright
Journal:  ACS Infect Dis       Date:  2015-01-15       Impact factor: 5.084

Review 6.  Role of the Environment in the Transmission of Antimicrobial Resistance to Humans: A Review.

Authors:  Patricia M C Huijbers; Hetty Blaak; Mart C M de Jong; Elisabeth A M Graat; Christina M J E Vandenbroucke-Grauls; Ana Maria de Roda Husman
Journal:  Environ Sci Technol       Date:  2015-09-28       Impact factor: 9.028

7.  Correlation between upstream human activities and riverine antibiotic resistance genes.

Authors:  Amy Pruden; Mazdak Arabi; Heather N Storteboom
Journal:  Environ Sci Technol       Date:  2012-10-12       Impact factor: 9.028

8.  Chromosomal beta-lactamase of Klebsiella oxytoca, a new class A enzyme that hydrolyzes broad-spectrum beta-lactam antibiotics.

Authors:  Y Arakawa; M Ohta; N Kido; M Mori; H Ito; T Komatsu; Y Fujii; N Kato
Journal:  Antimicrob Agents Chemother       Date:  1989-01       Impact factor: 5.191

Review 9.  Using the class 1 integron-integrase gene as a proxy for anthropogenic pollution.

Authors:  Michael R Gillings; William H Gaze; Amy Pruden; Kornelia Smalla; James M Tiedje; Yong-Guan Zhu
Journal:  ISME J       Date:  2014-12-12       Impact factor: 10.302

10.  Search Engine for Antimicrobial Resistance: A Cloud Compatible Pipeline and Web Interface for Rapidly Detecting Antimicrobial Resistance Genes Directly from Sequence Data.

Authors:  Will Rowe; Kate S Baker; David Verner-Jeffreys; Craig Baker-Austin; Jim J Ryan; Duncan Maskell; Gareth Pearce
Journal:  PLoS One       Date:  2015-07-21       Impact factor: 3.240

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Review 1.  Early detection monitoring for aquatic non-indigenous species: Optimizing surveillance, incorporating advanced technologies, and identifying research needs.

Authors:  Anett S Trebitz; Joel C Hoffman; John A Darling; Erik M Pilgrim; John R Kelly; Emily A Brown; W Lindsay Chadderton; Scott P Egan; Erin K Grey; Syed A Hashsham; Katy E Klymus; Andrew R Mahon; Jeffrey L Ram; Martin T Schultz; Carol A Stepien; James C Schardt
Journal:  J Environ Manage       Date:  2017-07-22       Impact factor: 6.789

2.  TCDD administered on activated carbon eliminates bioavailability and subsequent shifts to a key murine gut commensal.

Authors:  Robert D Stedtfeld; J Brett Sallach; Robert B Crawford; Tiffany M Stedtfeld; Maggie R Williams; Hassan Waseem; Cliff T Johnston; Hui Li; Brian J Teppen; Norbert E Kaminski; Stephen A Boyd; James M Tiedje; Syed A Hashsham
Journal:  Appl Microbiol Biotechnol       Date:  2017-08-15       Impact factor: 4.813

3.  Isothermal assay targeting class 1 integrase gene for environmental surveillance of antibiotic resistance markers.

Authors:  Robert D Stedtfeld; Tiffany M Stedtfeld; Hassen Waseem; Meridith Fitschen-Brown; Xueping Guo; Benli Chai; Maggie R Williams; Trevor Shook; Amanda Logan; Ally Graham; Jong-Chan Chae; Woo-Jun Sul; Jacob VanHouten; James R Cole; Gerben J Zylstra; James M Tiedje; Brad L Upham; Syed A Hashsham
Journal:  J Environ Manage       Date:  2017-04-29       Impact factor: 6.789

4.  A Human-Centered Platform for HIV Infection Reduction in New York: Development and Usage Analysis of the Ending the Epidemic (ETE) Dashboard.

Authors:  Ashish Joshi; Chioma Amadi; Benjamin Katz; Sarah Kulkarni; Denis Nash
Journal:  JMIR Public Health Surveill       Date:  2017-12-11

5.  Modulatory Influence of Segmented Filamentous Bacteria on Transcriptomic Response of Gnotobiotic Mice Exposed to TCDD.

Authors:  Robert D Stedtfeld; Benli Chai; Robert B Crawford; Tiffany M Stedtfeld; Maggie R Williams; Shao Xiangwen; Tomomi Kuwahara; James R Cole; Norbert E Kaminski; James M Tiedje; Syed A Hashsham
Journal:  Front Microbiol       Date:  2017-09-07       Impact factor: 5.640

6.  Primer set 2.0 for highly parallel qPCR array targeting antibiotic resistance genes and mobile genetic elements.

Authors:  Robert D Stedtfeld; Xueping Guo; Tiffany M Stedtfeld; Hongjie Sheng; Maggie R Williams; Kristin Hauschild; Santosh Gunturu; Leo Tift; Fang Wang; Adina Howe; Benli Chai; Daqiang Yin; James R Cole; James M Tiedje; Syed A Hashsham
Journal:  FEMS Microbiol Ecol       Date:  2018-09-01       Impact factor: 4.194

Review 7.  Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission.

Authors:  Dae-Wi Kim; Chang-Jun Cha
Journal:  Exp Mol Med       Date:  2021-03-01       Impact factor: 8.718

8.  High-Throughput Multiparallel Enteropathogen Detection via Nano-Liter qPCR.

Authors:  Jessica A Grembi; Koshlan Mayer-Blackwell; Stephen P Luby; Alfred M Spormann
Journal:  Front Cell Infect Microbiol       Date:  2020-07-15       Impact factor: 5.293

  8 in total

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