| Literature DB >> 26849299 |
Yuefeng Li1, F Jeffrey Dilworth2.
Abstract
Satellite cells comprise a pool of quiescent stem cells that repair muscle damage, but the mechanisms enforcing their quiescence are poorly defined. In this issue of Cell Stem Cell, Boonsanay et al. (2016) show that the histone methyltransferase Suv4-20H1 maintains satellite cell quiescence by promoting a heterochromatic state through transcriptional repression of the myogenic master regulator MyoD.Entities:
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Year: 2016 PMID: 26849299 DOI: 10.1016/j.stem.2016.01.009
Source DB: PubMed Journal: Cell Stem Cell ISSN: 1875-9777 Impact factor: 24.633