Literature DB >> 26849256

Single and Combined Exposure to Zinc- and Copper-Containing Welding Fumes Lead to Asymptomatic Systemic Inflammation.

Agnieszka Markert1, Ralf Baumann, Benjamin Gerhards, Monika Gube, Veronika Kossack, Thomas Kraus, Peter Brand.   

Abstract

OBJECTIVE: Recently, it has been shown that exposure to welding fumes containing both zinc and copper leads to asymptomatic systemic inflammation in humans as shown by an increase of blood C-reactive protein. In the present study, it was investigated which metal is responsible for this effect.
METHODS: Fifteen healthy male subjects were exposed under controlled conditions to welding fumes containing either zinc, or copper, or copper and zinc.
RESULTS: For each exposure blood C-reactive protein increased.
CONCLUSIONS: Copper- and zinc-containing welding fumes are able to induce systemic inflammation.

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Year:  2016        PMID： 26849256     DOI： 10.1097/JOM.0000000000000652

Source DB:  PubMed          Journal:  J Occup Environ Med        ISSN： 1076-2752            Impact factor:   2.162


  6 in total

1.  Systemic serum amyloid A as a biomarker for exposure to zinc and/or copper-containing metal fumes.

Authors:  R Baumann; M Gube; A Markert; S Davatgarbenam; V Kossack; B Gerhards; T Kraus; P Brand
Journal:  J Expo Sci Environ Epidemiol       Date:  2017-02-08       Impact factor: 5.563

2.  Precision multiparameter tracking of inflammation on timescales of hours to years using serial dried blood spots.

Authors:  Leigh Anderson; Morteza Razavi; Matthew E Pope; Richard Yip; L C Cameron; Adriana Bassini-Cameron; Terry W Pearson
Journal:  Bioanalysis       Date:  2020-04-07       Impact factor: 2.681

3.  Welding fume exposure is associated with inflammation: a global metabolomics profiling study.

Authors:  Sipeng Shen; Ruyang Zhang; Jinming Zhang; Yongyue Wei; Yichen Guo; Li Su; Feng Chen; David C Christiani
Journal:  Environ Health       Date:  2018-08-22       Impact factor: 5.984

4.  The pro-inflammatory stimulus of zinc- and copper-containing welding fumes in whole blood assay via protein tyrosine phosphatase 1B inhibition.

Authors:  Johannes Bleidorn; Hanif Alamzad-Krabbe; Benjamin Gerhards; Thomas Kraus; Peter Brand; Julia Krabbe; Christian Martin
Journal:  Sci Rep       Date:  2019-02-04       Impact factor: 4.379

5.  The human long noncoding RNAs CoroMarker, MALAT1, CDR1as, and LINC00460 in whole blood of individuals after controlled short-term exposure with ultrafine metal fume particles at workplace conditions, and in human macrophages in vitro.

Authors:  Theresa Scheurer; Jan Steffens; Agnieszka Markert; Miriam Du Marchie Sarvaas; Christoph Roderburg; Lothar Rink; Frank Tacke; Tom Luedde; Thomas Kraus; Ralf Baumann
Journal:  J Occup Med Toxicol       Date:  2022-08-01       Impact factor: 2.862

6.  Welding Fume Instillation in Isolated Perfused Mouse Lungs-Effects of Zinc- and Copper-Containing Welding Fumes.

Authors:  Julia Krabbe; Thomas Kraus; Hanif Krabbe; Christian Martin; Patrick Ziegler
Journal:  Int J Mol Sci       Date:  2022-08-12       Impact factor: 6.208
  6 in total

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