Literature DB >> 26843100

Approach to Isoindolinones, Isoquinolinones, and THIQs via Lewis Acid-Catalyzed Domino Strecker-Lactamization/Alkylations.

Sivasankaran Dhanasekaran1, Arun Suneja2, Vishnumaya Bisai2, Vinod K Singh2,1.   

Abstract

A one-pot, three-component synthesis of widely substituted isoindolinones and isoquinolinones, featuring a Lewis acid-catalyzed efficient Strecker reaction and lactamization sequence, affording products in good to high yields is reported. The method has also been extended to the synthesis of tetrahydroisoquinolines (THIQs) in high yields.

Entities:  

Year:  2016        PMID： 26843100     DOI： 10.1021/acs.orglett.5b03331

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Mechanochemical Lignin-Mediated Strecker Reaction.

Authors:  Saumya Dabral; Mathias Turberg; Andrea Wanninger; Carsten Bolm; José G Hernández
Journal:  Molecules       Date:  2017-01-17       Impact factor: 4.411

2.  Visible-Light-Enabled Aminocarbonylation of Unactivated Alkyl Iodides with Stoichiometric Carbon Monoxide for Application on Late-Stage Carbon Isotope Labeling.

Authors:  Malvika Sardana; Joakim Bergman; Cecilia Ericsson; Lee P Kingston; Magnus Schou; Christophe Dugave; Davide Audisio; Charles S Elmore
Journal:  J Org Chem       Date:  2019-12-11       Impact factor: 4.354

3.  Enantioselective Bifunctional Ammonium Salt-Catalyzed Syntheses of 3-CF3S-, 3-RS-, and 3-F-Substituted Isoindolinones.

Authors:  Andreas Eitzinger; Jan Otevrel; Victoria Haider; Antonio Macchia; Antonio Massa; Kirill Faust; Bernhard Spingler; Albrecht Berkessel; Mario Waser
Journal:  Adv Synth Catal       Date:  2021-02-17       Impact factor: 5.837

Review 4.  Isoindolinone Synthesis via One-Pot Type Transition Metal Catalyzed C-C Bond Forming Reactions.

Authors:  Risto Savela; Carolina Méndez-Gálvez
Journal:  Chemistry       Date:  2021-02-02       Impact factor: 5.236
  4 in total

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