| Literature DB >> 26842704 |
Belén Rodríguez-Sánchez1, M Jesús Ruiz-Serrano2, Adrián Ruiz3, Markus Timke4, Markus Kostrzewa4, Emilio Bouza5.
Abstract
Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has demonstrated its ability to promptly identify nontuberculous mycobacteria using the Mycobacteria Library v2.0. However, some species are particularly difficult to identify reliably using this database, providing a low log(score). In this study, the identification power of an updated Mycobacteria Library (v3.0) has been evaluated. Overall, 109 NTM isolates were analyzed with both databases. The v3.0 database allowed a high-level confidence in the identification [log(score) value, ≥1.8] of 91.7% of the isolates versus 83.5% with the v2.0 version (P< 0.01).Entities:
Mesh:
Year: 2016 PMID: 26842704 PMCID: PMC4809906 DOI: 10.1128/JCM.02760-15
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948