Literature DB >> 26842692

IV Acetaminophen Results in Lower Hospital Costs and Emergency Room Visits Following Bariatric Surgery: a Double-Blind, Prospective, Randomized Trial in a Single Accredited Bariatric Center.

Maher El Chaar1, Jill Stoltzfus2, Leonardo Claros2, Tara Wasylik2.   

Abstract

BACKGROUND: Postoperative pain control in bariatric surgery is challenging, despite use of intravenous (IV) narcotics. IV acetaminophen is one pain control alternative.
OBJECTIVE: The aim of this study was to investigate the economic impact of IV acetaminophen in bariatric surgery and its effect on patients' pain, satisfaction, and hospital length of stay.
METHODS: In a randomized controlled trial, Group 1 (treatment) received IV acetaminophen plus IV narcotics 30 min before surgery, then medication plus IV narcotics/PO narcotics for the remaining 18 h. Group 2 (control) received IV normal saline plus IV/PO narcotics. Patients underwent laparoscopic Roux-en-Y gastric bypass (LRYGB) or laparoscopic sleeve gastrectomy (SG). Primary outcomes included direct hospital costs, length of stay, postoperative pain, and patient satisfaction. Secondary outcomes included indirect costs, rescue narcotics dosage, and 30-day outcomes.
RESULTS: Mean direct hospital cost in the treatment group (n = 50) was $3089.18 versus $2991.62 for the control group (n = 50) (p > 0.05). Pain scores did not differ significantly (p = 0.61). After adjusting for surgery type, there was no significant difference in length of stay (p = 0.95). Significantly more control group patients incurred surgery-related indirect costs (10 versus 2%, p < 0.05), with greater presentation to the emergency department (ED) for abdominal pain (5/50 versus 1/50), yielding higher total indirect costs ($39,293 versus $13,185).
CONCLUSIONS: Using IV acetaminophen for postoperative pain management produced notable indirect cost savings and reduced ED visits in the first 30 days postoperatively, with good safety and tolerance. Decreased statistical power may have accounted for certain non-significant findings.

Entities:  

Keywords:  Bariatric surgery; Direct costs; Hospital length of stay; Indirect costs; Intravenous acetaminophen; Patient satisfaction; Postoperative pain control

Mesh:

Substances:

Year:  2016        PMID: 26842692     DOI: 10.1007/s11605-016-3088-0

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  26 in total

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2.  Fast track colorectal surgery.

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3.  Volume and outcome relationship in bariatric surgery in the laparoscopic era.

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4.  A prospective randomized trial of laparoscopic gastric bypass versus laparoscopic adjustable gastric banding for the treatment of morbid obesity: outcomes, quality of life, and costs.

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6.  First report from the American College of Surgeons Bariatric Surgery Center Network: laparoscopic sleeve gastrectomy has morbidity and effectiveness positioned between the band and the bypass.

Authors:  Matthew M Hutter; Bruce D Schirmer; Daniel B Jones; Clifford Y Ko; Mark E Cohen; Ryan P Merkow; Ninh T Nguyen
Journal:  Ann Surg       Date:  2011-09       Impact factor: 12.969

7.  Intravenous acetaminophen (paracetamol): comparable analgesic efficacy, but better local safety than its prodrug, propacetamol, for postoperative pain after third molar surgery.

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8.  Bariatric surgery worldwide 2003.

Authors:  Henry Buchwald; Stanley E Williams
Journal:  Obes Surg       Date:  2004-10       Impact factor: 4.129

9.  Introduction of laparoscopic bariatric surgery in England: observational population cohort study.

Authors:  Elaine M Burns; Haris Naseem; Alex Bottle; Antonio Ivan Lazzarino; Paul Aylin; Ara Darzi; Krishna Moorthy; Omar Faiz
Journal:  BMJ       Date:  2010-08-26

10.  Impact of bariatric surgery on health care costs of obese persons: a 6-year follow-up of surgical and comparison cohorts using health plan data.

Authors:  Jonathan P Weiner; Suzanne M Goodwin; Hsien-Yen Chang; Shari D Bolen; Thomas M Richards; Roger A Johns; Soyal R Momin; Jeanne M Clark
Journal:  JAMA Surg       Date:  2013-06       Impact factor: 14.766

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  6 in total

1.  A Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Acetaminophen on Hospital Length of Stay in Obese Individuals Undergoing Sleeve Gastrectomy.

Authors:  Farrell E Cooke; Jon D Samuels; Alfons Pomp; Farida Gadalla; Xian Wu; Cheguevara Afaneh; Gregory F Dakin; Peter A Goldstein
Journal:  Obes Surg       Date:  2018-10       Impact factor: 4.129

2.  Postoperative Pain and Opioid Consumption in the Acute Postoperative Period after Laparoscopic Gastrectomy.

Authors:  Mark C Kendall; Lucas J Castro-Alves
Journal:  J Gastrointest Surg       Date:  2018-04-11       Impact factor: 3.452

Review 3.  Multimodal Analgesia, Current Concepts, and Acute Pain Considerations.

Authors:  Erik M Helander; Bethany L Menard; Chris M Harmon; Ben K Homra; Alexander V Allain; Gregory J Bordelon; Melville Q Wyche; Ira W Padnos; Anna Lavrova; Alan D Kaye
Journal:  Curr Pain Headache Rep       Date:  2017-01

4.  The Effect of Scheduled Intravenous Acetaminophen in an Enhanced Recovery Protocol Pathway in Patients Undergoing Major Abdominal Procedures: A Prospective, Randomized, and Placebo-Controlled Clinical Trial.

Authors:  Kathirvel Subramaniam; Stephen A Esper; Kushanth Mallikarjun; Alec Dickson; Kristin Ruppert DrPH; Tomas Drabek; Hesper Wong; Jennifer Holder-Murray
Journal:  Pain Med       Date:  2022-01-03       Impact factor: 3.637

5.  Intravenous Acetaminophen Versus Placebo in Post-bariatric Surgery Multimodal Pain Management: a Meta-analysis of Randomized Controlled Trials.

Authors:  Yung Lee; James Yu; Aristithes G Doumouras; Vahid Ashoorion; Scott Gmora; Mehran Anvari; Dennis Hong
Journal:  Obes Surg       Date:  2019-04       Impact factor: 4.129

6.  Estimating the Effect of Intravenous Acetaminophen for Postoperative Pain Management on Length of Stay and Inpatient Hospital Costs.

Authors:  E Eve Shaffer; An Pham; Robert L Woldman; Andrew Spiegelman; Scott A Strassels; George J Wan; Thomas Zimmerman
Journal:  Adv Ther       Date:  2016-11-09       Impact factor: 3.845

  6 in total

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