Literature DB >> 26841639

Primary Dysmenorrhea in Adolescents: Prevalence, Impact and Recent Knowledge.

Vincenzo De Sanctis, Ashraf Soliman, Sergio Bernasconi, Luigi Bianchin, Gianni Bona, Mauro Bozzola, Fabio Buzi, Carlo De Sanctis, Giorgio Tonini, Franco Rigon, Egle Perissinotto.   

Abstract

BACKGROUND AND OBJECTIVES: Dysmenorrhea is commonly categorized into two types; primary and secondary. Primary dysmenorrhea (PD) is the focus of this review. PD is defined as painful menses with cramping sensation in the lower abdomen that is often accompanied by other symptoms, such as sweating, headache, nausea, vomiting, diarrhea, and tremulousness. All these symptoms occur just before or during the menses in women with normal pelvic anatomy. In adolescents the prevalence of PD varies between 16% and 93%, with severe pain perceived in 2% to 29% of the studied girls. Several studies suggest that severe menstrual pain is associated with absenteeism from school or work and limitation of other daily activities. One-third to one-half of females with PD are missing school or work at least once per cycle, and more frequently in 5% to 14% of them. The wide variation in the prevalence rates may be attributed to the use of selected groups of subjects. Many risk factors are associated with increased severity of dysmenorrhea including earlier age at menarche, long menstrual periods, heavy menstrual flow, smoking and positive family history. Young women using oral contraceptive pills (OCP) report less severe dysmenorrhea. The considerably high prevalence of dysmenorrhea among adolescents verified that this condition is a significant public health problem that requires great attention. SUMMARY OF MAIN
RESULTS: Many methodological problems are encountered during quantifying and grading severity of pain related to dysmenorrhea. Quantifying and assessment tools depend on women's self-reporting with potential bias. There is a scarcity of longitudinal studies on the natural history of dysmenorrhea as well as the possible effects of many modifiable risk factors. In addition, the duration of follow-up in the available studies is relatively short. Therefore, several aspects are still open for research. Medical treatment for dysmenorrhea includes anti-inflammatory drugs (NSAIDs), OCP or surgical intervention. The efficacy of conventional treatments using NSAIDs and OCP is high. However, failure rate may reach up to 20% to 25%, besides the occurrence of drug-associated adverse effects. Only 6% of adolescents receive medical advice to treat dysmenorrhea while 70% practice self-management. Unfortunately, some girls even abuse these medications (non-therapeutic high doses) for quick pain relief. The persistence of dysmenorrhea despite the use of OCP and/or NSAIDs drugs is a strong indicator of an organic pelvic disease. This condition mandates an appropriate referral to a gynecologist with proper laparoscopic diagnosis of endometriosis and/or other pelvic diseases.
CONCLUSIONS: Dysmenorrhea is an important health problem for adolescents, school and occupational as well as practitioners that adversely affects the daily activities and quality of life for adolescent women. The accurate prevalence of dysmenorrhea is difficult to establish due to the variety of diagnostic criteria and the subjective nature of the symptoms. In adolescents, moderate to severe dysmenorrhea that affects lifestyle and does not respond to medical treatment requires professional attention and proper diagnosis of possible underlying pelvic disease. Therefore, adolescent care providers should be more knowledgeable and actively involved in the care of dysmenorrhea.

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Year:  2015        PMID: 26841639

Source DB:  PubMed          Journal:  Pediatr Endocrinol Rev        ISSN: 1565-4753


  30 in total

1.  Network Pharmacology-Based Approach to Investigate the Analgesic Efficacy and Molecular Targets of Xuangui Dropping Pill for Treating Primary Dysmenorrhea.

Authors:  Jihan Huang; Lei Li; Fan Cheung; Ning Wang; Yunfei Li; Zhenyu Fan; Fang Yin; Juan Yang; Rui Gao; Yingchun He; Yibin Feng
Journal:  Evid Based Complement Alternat Med       Date:  2017-10-08       Impact factor: 2.629

Review 2.  Dysmenorrhea and related disorders.

Authors:  Mariagiulia Bernardi; Lucia Lazzeri; Federica Perelli; Fernando M Reis; Felice Petraglia
Journal:  F1000Res       Date:  2017-09-05

3.  The Impact of Endometriosis on the Quality of Life and the Incidence of Depression-A Cohort Study.

Authors:  Damian Warzecha; Iwona Szymusik; Miroslaw Wielgos; Bronislawa Pietrzak
Journal:  Int J Environ Res Public Health       Date:  2020-05-21       Impact factor: 3.390

4.  Lifestyle and prevalence of dysmenorrhea among Spanish female university students.

Authors:  Elia Fernández-Martínez; María Dolores Onieva-Zafra; María Laura Parra-Fernández
Journal:  PLoS One       Date:  2018-08-10       Impact factor: 3.240

5.  Dysmenorrhoea among students aged 18-45 years attending University in Uganda: A cross-sectional multicenter study of three Universities in Uganda.

Authors:  Rose Mary Nakame; Frank Kiwanuka; Afayo Robert
Journal:  Nurs Open       Date:  2018-09-27

6.  WaLIDD score, a new tool to diagnose dysmenorrhea and predict medical leave in university students.

Authors:  Aníbal A Teherán; Luis Gabriel Piñeros; Fabián Pulido; María Camila Mejía Guatibonza
Journal:  Int J Womens Health       Date:  2018-01-17

7.  Prevalence of dysmenorrhea and predictors of its pain intensity among Palestinian female university students.

Authors:  Heba A Abu Helwa; Areen A Mitaeb; Suha Al-Hamshri; Waleed M Sweileh
Journal:  BMC Womens Health       Date:  2018-01-15       Impact factor: 2.809

8.  Comparison of the efficacy and safety of non-steroidal anti-inflammatory drugs for patients with primary dysmenorrhea: A network meta-analysis.

Authors:  Xuan Feng; Xiaoyun Wang
Journal:  Mol Pain       Date:  2018-03-27       Impact factor: 3.395

9.  Effects of herb-partitioned moxibustion for primary dysmenorrhea: A protocol for systematic review and meta-analysis.

Authors:  Fengjun Ma; Xiao Yan; Yanpu Yu; Dongqing Du; Shujing Li; Chen Chen; Xiaobin Zhang; Zhibin Dong; Yuxia Ma; Yuning Ma
Journal:  Medicine (Baltimore)       Date:  2020-07-17       Impact factor: 1.817

10.  Heat therapy for primary dysmenorrhea: A systematic review and meta-analysis of its effects on pain relief and quality of life.

Authors:  Junyoung Jo; Sun Haeng Lee
Journal:  Sci Rep       Date:  2018-11-02       Impact factor: 4.379

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