Literature DB >> 26839520

Can Serum Testosterone Be Used as a Marker of Overall Health?

Michael A Mederos1, Aaron M Bernie2, Jason M Scovell1, Ranjith Ramasamy1.   

Abstract

Low serum testosterone has been associated with obesity, type 2 diabetes, metabolic syndrome, and atherosclerosis. Individuals with these comorbidities are at increased risk of premature death and other adverse health effects. Clinical data portend low testosterone as a risk factor for developing these conditions which are supported by the hypogonadal-obesity-adipocytokine hypothesis. The authors support comprehensive evaluation for these comorbid conditions in men found to have low serum testosterone.

Entities:  

Keywords:  Aging male; Androgen deficiency; Cardiovascular disease; Comorbidities; Diabetes

Year:  2015        PMID： 26839520      PMCID： PMC4735669     

Source DB:  PubMed          Journal:  Rev Urol        ISSN： 1523-6161


  33 in total

1.  Low sex hormone-binding globulin, total testosterone, and symptomatic androgen deficiency are associated with development of the metabolic syndrome in nonobese men.

Authors:  Varant Kupelian; Stephanie T Page; Andre B Araujo; Thomas G Travison; William J Bremner; John B McKinlay
Journal:  J Clin Endocrinol Metab       Date:  2006-01-04       Impact factor: 5.958

2.  Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study.

Authors:  Kay-Tee Khaw; Mitch Dowsett; Elizabeth Folkerd; Sheila Bingham; Nicholas Wareham; Robert Luben; Ailsa Welch; Nicholas Day
Journal:  Circulation       Date:  2007-11-26       Impact factor: 29.690

3.  The association between premature coronary artery disease and level of testosterone in young adult males.

Authors:  Abdulhakim Alkamel; Akbar Shafiee; Arash Jalali; Mohammadali Boroumand; Younes Nozari
Journal:  Arch Iran Med       Date:  2014-08       Impact factor: 1.354

Review 4.  Adipokines: a link between obesity and cardiovascular disease.

Authors:  Kazuto Nakamura; José J Fuster; Kenneth Walsh
Journal:  J Cardiol       Date:  2013-12-16       Impact factor: 3.159

5.  The relative contributions of aging, health, and lifestyle factors to serum testosterone decline in men.

Authors:  Thomas G Travison; Andre B Araujo; Varant Kupelian; Amy B O'Donnell; John B McKinlay
Journal:  J Clin Endocrinol Metab       Date:  2006-12-05       Impact factor: 5.958

Review 6.  Inflammation, stress, and diabetes.

Authors:  Kathryn E Wellen; Gökhan S Hotamisligil
Journal:  J Clin Invest       Date:  2005-05       Impact factor: 14.808

7.  Lower serum testosterone is independently associated with insulin resistance in non-diabetic older men: the Health In Men Study.

Authors:  Bu B Yeap; S A Paul Chubb; Zoë Hyde; Konrad Jamrozik; Graeme J Hankey; Leon Flicker; Paul E Norman
Journal:  Eur J Endocrinol       Date:  2009-08-06       Impact factor: 6.664

Review 8.  Testosterone and metabolic syndrome: a meta-analysis study.

Authors:  Giovanni Corona; Matteo Monami; Giulia Rastrelli; Antonio Aversa; Yuliya Tishova; Farid Saad; Andrea Lenzi; Gianni Forti; Edoardo Mannucci; Mario Maggi
Journal:  J Sex Med       Date:  2010-08-30       Impact factor: 3.802

9.  Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men.

Authors:  David E Laaksonen; Leo Niskanen; Kari Punnonen; Kristiina Nyyssönen; Tomi-Pekka Tuomainen; Veli-Pekka Valkonen; Riitta Salonen; Jukka T Salonen
Journal:  Diabetes Care       Date:  2004-05       Impact factor: 19.112

Review 10.  Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis.

Authors:  Katherine M Flegal; Brian K Kit; Heather Orpana; Barry I Graubard
Journal:  JAMA       Date:  2013-01-02       Impact factor: 56.272
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  1 in total

Review 1.  Andrology: Ibuprofen and hypogonadism - bench to bedside to misinterpreted hype?

Authors:  Ajay K Nangia; Derek Jensen
Journal:  Nat Rev Urol       Date:  2018-03-06       Impact factor: 14.432
  1 in total

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