Literature DB >> 2683840

Eosinophils in atopic dermatitis.

K M Leiferman1.   

Abstract

The eosinophilic granulocyte is commonly associated with allergic inflammation. Although blood eosinophilia frequently accompanies atopic dermatitis, accumulation of tissue eosinophils is not prominent. Recent studies have elucidated the structure, content, and activities of the eosinophil. In addition, immunofluorescence localization of eosinophil granulate proteins has shown that eosinophils disrupt in tissue depositing toxic granule proteins in several diseases. Here, evidence for eosinophil degranulation in atopic dermatitis is presented and mechanisms whereby eosinophil degranulation may mediate pathophysiologic effects in atopic dermatitis and related conditions are discussed.

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Year:  1989        PMID： 2683840

Source DB:  PubMed          Journal:  Allergy        ISSN： 0105-4538            Impact factor:   13.146


  8 in total

1.  Chemokine-induced eosinophil recruitment. Evidence of a role for endogenous eotaxin in an in vivo allergy model in mouse skin.

Authors:  M M Teixeira; T N Wells; N W Lukacs; A E Proudfoot; S L Kunkel; T J Williams; P G Hellewell
Journal:  J Clin Invest       Date:  1997-10-01       Impact factor: 14.808

2.  The development of a sensitive and specific ELISA for mouse eosinophil peroxidase: assessment of eosinophil degranulation ex vivo and in models of human disease.

Authors:  Sergei I Ochkur; John Dongil Kim; Cheryl A Protheroe; Dana Colbert; Redwan Moqbel; Paige Lacy; James J Lee; Nancy A Lee
Journal:  J Immunol Methods       Date:  2011-10-12       Impact factor: 2.303

3.  Eosinophil granule proteins expressed in ocular cicatricial pemphigoid.

Authors:  A Heiligenhaus; J Schaller; S Mauss; S Engelbrecht; J E Dutt; C S Foster; K P Steuhl
Journal:  Br J Ophthalmol       Date:  1998-03       Impact factor: 4.638

Review 4.  Human versus mouse eosinophils: "that which we call an eosinophil, by any other name would stain as red".

Authors:  James J Lee; Elizabeth A Jacobsen; Sergei I Ochkur; Michael P McGarry; Rachel M Condjella; Alfred D Doyle; Huijun Luo; Katie R Zellner; Cheryl A Protheroe; Lian Willetts; William E Lesuer; Dana C Colbert; Richard A Helmers; Paige Lacy; Redwan Moqbel; Nancy A Lee
Journal:  J Allergy Clin Immunol       Date:  2012-09       Impact factor: 10.793

5.  Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis.

Authors:  Q Hamid; M Boguniewicz; D Y Leung
Journal:  J Clin Invest       Date:  1994-08       Impact factor: 14.808

6.  Assessment of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Atopic Dermatitis Patients.

Authors:  Ying Jiang; Wencong Ma
Journal:  Med Sci Monit       Date:  2017-03-17

7.  Tissue eosinophilia induced by recombinant human interleukin-5 in the hamster cheek pouch membrane.

Authors:  M Minnicozzi; W N Durán; D Kim; G J Gleich; J Wagner; R W Egan
Journal:  Mediators Inflamm       Date:  1995       Impact factor: 4.711

Review 8.  Biochemical and pathological studies on peroxidases -an updated review.

Authors:  Amjad A Khan; Arshad H Rahmani; Yousef H Aldebasi; Salah M Aly
Journal:  Glob J Health Sci       Date:  2014-05-13
  8 in total

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