| Literature DB >> 26837734 |
Xiaolong Qi1, Li Zhang2, Xiaojie Lu3.
Abstract
The role of the epithelial-to-mesenchymal transition (EMT) in cancer progression is a long-debated issue. Recent evidence shows that EMT is not a prerequisite for cancer metastasis, but does confer chemoresistance. Future studies are needed to profile EMT events in different cancer types and under different circumstances to explore their potentials as therapeutic targets.Entities:
Keywords: cancer metastasis; chemoresistance; epithelial-to-mesenchymal transition
Mesh:
Year: 2016 PMID: 26837734 DOI: 10.1016/j.tips.2016.01.002
Source DB: PubMed Journal: Trends Pharmacol Sci ISSN: 0165-6147 Impact factor: 14.819