Literature DB >> 26835158

Ubiquitin-Specific Proteases as Druggable Targets.

Mindy I Davis1, Anton Simeonov1.   

Abstract

Entities:  

Year:  2015        PMID： 26835158      PMCID： PMC4729384     

Source DB:  PubMed          Journal:  Drug Target Rev        ISSN： 2059-1349


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  50 in total

1.  Comprehensive analysis of kinase inhibitor selectivity.

Authors:  Mindy I Davis; Jeremy P Hunt; Sanna Herrgard; Pietro Ciceri; Lisa M Wodicka; Gabriel Pallares; Michael Hocker; Daniel K Treiber; Patrick P Zarrinkar
Journal:  Nat Biotechnol       Date:  2011-10-30       Impact factor: 54.908

2.  The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

Authors:  Alex C Faesen; Mark P A Luna-Vargas; Paul P Geurink; Marcello Clerici; Remco Merkx; Willem J van Dijk; Dharjath S Hameed; Farid El Oualid; Huib Ovaa; Titia K Sixma
Journal:  Chem Biol       Date:  2011-12-23

3.  Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes.

Authors:  Matteo Colombo; Stefania Vallese; Ilaria Peretto; Xavier Jacq; Jean-Christophe Rain; Frédéric Colland; Philippe Guedat
Journal:  ChemMedChem       Date:  2010-04-06       Impact factor: 3.466

4.  Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne.

Authors:  Anja Bremm; Stefan M V Freund; David Komander
Journal:  Nat Struct Mol Biol       Date:  2010-07-11       Impact factor: 15.369

5.  The deubiquitinase USP28 stabilizes LSD1 and confers stem-cell-like traits to breast cancer cells.

Authors:  Yadi Wu; Yifan Wang; Xiuwei H Yang; Tiebang Kang; Yongxiang Zhao; Chi Wang; B Mark Evers; Binhua P Zhou
Journal:  Cell Rep       Date:  2013-09-26       Impact factor: 9.423

6.  The isopeptidase USP2a protects human prostate cancer from apoptosis.

Authors:  Carmen Priolo; Dan Tang; Mohan Brahamandan; Barbara Benassi; Ewa Sicinska; Shuji Ogino; Antonella Farsetti; Alessandro Porrello; Stephen Finn; Johann Zimmermann; Phillip Febbo; Massimo Loda
Journal:  Cancer Res       Date:  2006-09-01       Impact factor: 12.701

7.  Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains.

Authors:  David Komander; Francisca Reyes-Turcu; Julien D F Licchesi; Peter Odenwaelder; Keith D Wilkinson; David Barford
Journal:  EMBO Rep       Date:  2009-04-17       Impact factor: 8.807

8.  Enhancement of proteasome activity by a small-molecule inhibitor of USP14.

Authors:  Byung-Hoon Lee; Min Jae Lee; Soyeon Park; Dong-Chan Oh; Suzanne Elsasser; Ping-Chung Chen; Carlos Gartner; Nevena Dimova; John Hanna; Steven P Gygi; Scott M Wilson; Randall W King; Daniel Finley
Journal:  Nature       Date:  2010-09-09       Impact factor: 49.962

9.  The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network.

Authors:  Min Sup Song; Leonardo Salmena; Arkaitz Carracedo; Ainara Egia; Francesco Lo-Coco; Julie Teruya-Feldstein; Pier Paolo Pandolfi
Journal:  Nature       Date:  2008-08-20       Impact factor: 49.962

10.  Deubiquitylation and stabilization of PTEN by USP13.

Authors:  Peijing Zhang; Yongkun Wei; Jinsong Zhang; Hai-Long Piao; Wenqi Wang; Subbareddy Maddika; Min Wang; Dahu Chen; Yutong Sun; Mien-Chie Hung; Junjie Chen; Li Ma
Journal:  Nat Cell Biol       Date:  2013-11-24       Impact factor: 28.824
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  12 in total

1.  USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors.

Authors:  Kah Suan Lim; Heng Li; Emma A Roberts; Emily F Gaudiano; Connor Clairmont; Larissa Alina Sambel; Karthikeyan Ponnienselvan; Jessica C Liu; Chunyu Yang; David Kozono; Kalindi Parmar; Timur Yusufzai; Ning Zheng; Alan D D'Andrea
Journal:  Mol Cell       Date:  2018-12-20       Impact factor: 17.970

2.  Ubiquitin-specific protease 26 (USP26) is not essential for mouse gametogenesis and fertility.

Authors:  Natalia Felipe-Medina; Laura Gómez-H; Yazmine B Condezo; Manuel Sanchez-Martín; José Luis Barbero; Isabel Ramos; Elena Llano; Alberto M Pendás
Journal:  Chromosoma       Date:  2019-03-18       Impact factor: 4.316

Review 3.  Deubiquitinases: Pro-oncogenic Activity and Therapeutic Targeting in Blood Malignancies.

Authors:  Blanca T Gutierrez-Diaz; Wei Gu; Panagiotis Ntziachristos
Journal:  Trends Immunol       Date:  2020-03-02       Impact factor: 16.687

4.  Ubiquitin-Proteasome Axis, Especially Ubiquitin-Specific Protease-17 (USP17) Gene Family, is a Potential Target for Epithelial-Mesenchymal Transition in High-Grade Serous Ovarian Cancer.

Authors:  Nuri Yildirim; Gizem Calibasi Kocal; Zerrin Isik; Bahadır Saatli; Ugur Saygili; Tugba Uysal; Cagnur Ulukus; Meral Koyuncuoglu; Hulya Ellidokuz; Yasemin Basbinar
Journal:  Reprod Sci       Date:  2018-09-09       Impact factor: 3.060

5.  MicroRNA-17 Suppresses TNF-α Signaling by Interfering with TRAF2 and cIAP2 Association in Rheumatoid Arthritis Synovial Fibroblasts.

Authors:  Nahid Akhtar; Anil Kumar Singh; Salahuddin Ahmed
Journal:  J Immunol       Date:  2016-08-17       Impact factor: 5.422

6.  Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin.

Authors:  Jongchan Kim; Fatemeh Alavi Naini; Yutong Sun; Li Ma
Journal:  Am J Cancer Res       Date:  2018-09-01       Impact factor: 6.166

7.  Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes.

Authors:  Laura M Doherty; Caitlin E Mills; Sarah A Boswell; Xiaoxi Liu; Charles Tapley Hoyt; Benjamin Gyori; Sara J Buhrlage; Peter K Sorger
Journal:  Elife       Date:  2022-06-23       Impact factor: 8.713

8.  Increase in the nuclear localization of PTEN by the Toxoplasma GRA16 protein and subsequent induction of p53-dependent apoptosis and anticancer effect.

Authors:  Sang-Gyun Kim; Seung-Hwan Seo; Ji-Hun Shin; Jung-Pyo Yang; Sang Hyung Lee; Eun-Hee Shin
Journal:  J Cell Mol Med       Date:  2019-03-04       Impact factor: 5.310

9.  Inhibiting USP14 ameliorates inflammatory responses in trophoblast cells by suppressing MAPK/NF-κB signaling.

Authors:  Yingzi Zhao; Fang Zong
Journal:  Immun Inflamm Dis       Date:  2021-06-05

10.  Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes.

Authors:  Wioletta Rut; Mikolaj Zmudzinski; Scott J Snipas; Miklos Bekes; Tony T Huang; Marcin Drag
Journal:  Chem Sci       Date:  2020-05-27       Impact factor: 9.825
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