| Literature DB >> 26835098 |
Saagar Mahida1, Frederic Sacher1, Nicolas Derval1, Benjamin Berte1, Seigo Yamashita1, Darren Hooks1, Arnaud Denis1, Sana Amraoui1, Meleze Hocini1, Michel Haissaguerre1, Pierre Jais1.
Abstract
Over the past few decades, significant progress has been made in understanding the mechanistic basis of atrial fibrillation (AF). One of the most important discoveries in this context has been that pulmonary veins (PV) play a prominent role in the pathogenesis of AF. PV isolation has since become the most widely used technique for treatment of paroxysmal AF. Multiple studies have demonstrated that the electrophysiological and anatomical characteristics of PVs create a proarrhythmogenic substrate. The following review discusses the mechanistic links between PVs and AF.Entities:
Keywords: Pulmonary vein isolation; ablation; atrial fibrillation; pulmonary vein electrophysiology; pulmonary vein histology
Year: 2015 PMID: 26835098 PMCID: PMC4711542 DOI: 10.15420/aer.2015.4.1.40
Source DB: PubMed Journal: Arrhythm Electrophysiol Rev ISSN: 2050-3369