Literature DB >> 26834904

Acquired hemophilia A: A rare cause of gross hematuria.

Gregory W Hosier1, Ross J Mason2, K Sue Robinson3, Gregory G Bailly2.   

Abstract

Acquired hemophilia A is a rare condition caused by spontaneous development of factor VIII inhibitor. This condition most commonly presents with multiple hemorrhagic symptoms and isolated hematuria is exceedingly rare. Early diagnosis is important, as this condition carries a high mortality rate (13-22%). We present a case of an 82-year-old man with isolated hematuria caused by a factor VIII inhibitor who was successfully treated with recombinant activated factor VII concentrate, as well as prednisone and cyclophosphamide.

Entities:  

Year:  2015        PMID： 26834904      PMCID： PMC4707916          DOI： 10.5489/cuaj.3306

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN： 1911-6470            Impact factor:   1.862


  15 in total

Review 1.  Acquired factor VIII inhibitor in a patient with adenocarcinoma of the lung.

Authors:  H Kondo; T Shigekiyo; A Kojima; S Saito; N Saijo
Journal:  Jpn J Clin Oncol       Date:  1992-02       Impact factor: 3.019

2.  Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation.

Authors:  Peter W Collins; Sybil Hirsch; Trevor P Baglin; Gerard Dolan; John Hanley; Michael Makris; David M Keeling; Ri Liesner; Simon A Brown; Charles R M Hay
Journal:  Blood       Date:  2006-10-17       Impact factor: 22.113

3.  Massive hematuria due to acquired factor VIII inhibitor. Treatment with cyclophosphamide.

Authors:  E A Waltke; S C Jacobs; C V Hussey; R K Lawson
Journal:  Urology       Date:  1981-12       Impact factor: 2.649

4.  Factor VIII inhibitor and bronchogenic carcinoma.

Authors:  S A Al-Ismail; D H Parry; C U Moisey; A L Bloom
Journal:  Thromb Haemost       Date:  1979-04-23       Impact factor: 5.249

5.  Acquired hemophilia. A natural history study of 16 patients with factor VIII inhibitors receiving little or no therapy.

Authors:  R Lottenberg; T B Kentro; C S Kitchens
Journal:  Arch Intern Med       Date:  1987-06

Review 6.  Acquired hemophilia due to factor VIII inhibitors in 34 patients.

Authors:  P Bossi; J Cabane; J Ninet; R Dhote; T Hanslik; O Chosidow; C Jouan-Flahault; M H Horellou; F Leynadier; E Liozon; J Pouchot; J P Robin; F Sanderson; A Schaeffer; D Sicard; F Staikowsky; B Wechsler; R Zittoun
Journal:  Am J Med       Date:  1998-11       Impact factor: 4.965

7.  A survey of 215 non-hemophilic patients with inhibitors to Factor VIII.

Authors:  D Green; K Lechner
Journal:  Thromb Haemost       Date:  1981-06-30       Impact factor: 5.249

Review 8.  Acquired hemophilia presenting as profound hematuria: evaluation, diagnosis, and management of elusive cause of bleeding in the emergency department setting.

Authors:  Aryeh Shander; Christopher Walsh; Heatherlee Bailey; Caroline Cromwell
Journal:  J Emerg Med       Date:  2013-04-30       Impact factor: 1.484

9.  [Macrohaematuria post-partum: an unusual case of acquired haemophilia after pregnancy].

Authors:  M A Prencipe; M D'Errico; G Di Giorgio; G Gatta; A Gesuete; M Nobile; C Stallone
Journal:  G Ital Nefrol       Date:  2002 Mar-Apr

10.  Acquired factor VIII inhibitor syndrome: A rare cause of hematuria.

Authors:  Muthuvel Seral Kannan; Thallur Ramakrishnan Raj Kumar; Srinivasan Subramanian
Journal:  Indian J Urol       Date:  2015 Jan-Mar
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