| Literature DB >> 26833581 |
Johannes B Ernst1, Andreas Rühling1, Birgit Wibbeling1, Frank Glorius2.
Abstract
The first trichloromethylthiolation of a broad range of indoles and pyrroles is reported employing bench-stable N-trichloromethylthiosaccharin as reagent. This methodology is highly regioselective, exhibits high functional group tolerance, and provides access to two previously unknown classes of potentially bioactive compounds.Entities:
Keywords: bioactive compounds; electrophilic substitution; heterocycles; organic chemistry; trichloromethylthiolation
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Year: 2016 PMID： 26833581 DOI： 10.1002/chem.201600377
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236