| Literature DB >> 26833561 |
L Poiteau1,2, A Soulier1,2, I Rosa3, F Roudot-Thoraval2,4, C Hézode2,5, J-M Pawlotsky1,2, S Chevaliez1,2.
Abstract
Rapid diagnostic tests (RDTs) represent an attractive alternative to enzyme immunoassays. A total of 207 individuals, including 68 HCV-seronegative subjects, 10 patients with resolved infection and 129 patients with chronic HCV infection, were studied. The specificity of RDT detection of anti-HCV antibodies in whole blood was 100% with the four RDTs tested: OraQuick(®) HCV Rapid Antibody Test, First Response HCV Card Test, ASSURE HCV Rapid Test and MultiSure HCV Antibody Assay. Their diagnostic sensitivity varied between 98.6% and 100%. RDT detection of anti-HCV antibody in whole blood collected on dried blood spots appears to be a promising new tool for broadscale screening of HCV infection in high- to medium-risk populations.Entities:
Keywords: anti-HCV antibodies; hepatitis C; rapid diagnostic test; screening
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Year: 2016 PMID： 26833561 DOI： 10.1111/jvh.12501
Source DB: PubMed Journal: J Viral Hepat ISSN： 1352-0504 Impact factor: 3.728