Literature DB >> 26831315

Relationship between pulmonary function and degree of spinal deformity, location of apical vertebrae and age among adolescent idiopathic scoliosis patients.

Joehaimey Johari1,2, Mohd Ariff Sharifudin2,3, Azriani Ab Rahman4, Ahmad Sabri Omar2, Ahmad Tajudin Abdullah1, Sobri Nor2, Weii Cheak Lam1, Mohd Imran Yusof5.   

Abstract

INTRODUCTION: This retrospective review aimed to examine the relationship between preoperative pulmonary function and the Cobb angle, location of apical vertebrae and age in adolescent idiopathic scoliosis (AIS). To our knowledge, there have been no detailed analyses of preoperative pulmonary function in relation to these three factors in AIS.
METHODS: A total of 38 patients with thoracic or thoracolumbar scoliosis were included. Curvature of spinal deformity was measured using the Cobb method. Forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were used to evaluate preoperative pulmonary function. Statistical methods were used to analyse the relationship between preoperative pulmonary function and the factors that may contribute to poor pulmonary function.
RESULTS: The mean age of the patients was 16.68 ± 6.04 years. An inverse relationship was found between the degree of the Cobb angle and FVC as well as FEV1; however, the relationships were not statistically significant (p = 0.057 and p = 0.072, respectively). There was also a trend towards a significant negative correlation between the thoracic curve and FVC (p = 0.014). Patients with larger thoracic curves had lower pulmonary function. A one-year increase in age significantly decreased FVC by 1.092 units (p = 0.044). No significant relationship between age and preoperative FEV1 was found. The median FVC was significantly higher in patients with affected apical vertebrae located at levels L1-L3 than at T6-T8 or T9-T12 (p = 0.006).
CONCLUSION: Lung function impairment was seen in more severe spinal deformities, proximally-located curvature and older patients.
Copyright © Singapore Medical Association.

Entities:  

Keywords:  apical vertebra; cobb angle; idiopathic scoliosis; pulmonary function; spinal deformity

Mesh:

Year:  2016        PMID: 26831315      PMCID: PMC4728701          DOI: 10.11622/smedj.2016009

Source DB:  PubMed          Journal:  Singapore Med J        ISSN: 0037-5675            Impact factor:   1.858


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