Literature DB >> 26831178

Comparison of thermal and mechanical quantitative sensory testing in client-owned dogs with chronic naturally occurring pain and normal dogs.

Mila Freire1, David Knazovicky2, Beth Case2, Andrea Thomson2, B Duncan X Lascelles3.   

Abstract

Detecting dogs with central sensitization (CS) secondary to chronic pain is hampered by the current inability to measure this condition. The current study aimed to use quantitative sensory testing (QST) to measure (CS) in normal dogs and dogs with painful degenerative joint disease (DJD). It was hypothesized that QST would differ between these two groups of animals. Mechanical and thermal sensory thresholds obtained in animals with DJD-associated pain on two time points 28 days apart were compared with those of normal dogs. Values of sensory thresholds in DJD dogs obtained 28 days after the first evaluation were significantly lower than the results on the first day of evaluation but no differences were found when these results were compared with those of normal dogs. In conclusion, whether QST is different between dogs with chronic pain and normal dogs needs further investigation using a larger group of animals and age, weight and sex matched groups.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Canine; Central Sensitization; Chronic pain; Mechanical sensory threshold; Thermal sensory threshold

Mesh:

Year:  2016        PMID: 26831178     DOI: 10.1016/j.tvjl.2016.01.005

Source DB:  PubMed          Journal:  Vet J        ISSN: 1090-0233            Impact factor:   2.688


  5 in total

1.  Investigating the Role of Artemin and Its Cognate Receptor, GFRα3, in Osteoarthritis Pain.

Authors:  Laura Minnema; Ankita Gupta; Santosh K Mishra; B Duncan X Lascelles
Journal:  Front Neurosci       Date:  2022-01-27       Impact factor: 4.677

2.  Long-term postoperative pain evaluation in dogs with thoracolumbar intervertebral disk herniation after hemilaminectomy.

Authors:  Natalia Zidan; Julia Medland; Natasha Olby
Journal:  J Vet Intern Med       Date:  2020-05-28       Impact factor: 3.333

3.  Investigation of sensory thresholds in Cavalier King Charles Spaniels with and without Chiari-like malformations and syringomyelia.

Authors:  Courtney R Sparks; Angela Gorney; Kim Williams; Emily H Griffith; Sofia Cerda-Gonzalez; B Duncan X Lascelles; Natasha J Olby
Journal:  J Vet Intern Med       Date:  2018-10-11       Impact factor: 3.333

4.  Frunevetmab, a felinized anti-nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats.

Authors:  Margaret E Gruen; Jamie A E Myers; Jezaniah-Kira S Tena; Csilla Becskei; Dawn M Cleaver; B Duncan X Lascelles
Journal:  J Vet Intern Med       Date:  2021-11-01       Impact factor: 3.333

5.  Reasons for Exclusion of Apparently Healthy Mature Adult and Senior Dogs From a Clinical Trial.

Authors:  Nicole H Gibbs; Hannah Michalski; Daniel E L Promislow; Matt Kaeberlein; Kate E Creevy
Journal:  Front Vet Sci       Date:  2021-06-02
  5 in total

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