Literature DB >> 26831054

Case Files of the University of Massachusetts Toxicology Fellowship: Does This Smoke Inhalation Victim Require Treatment with Cyanide Antidote?

Eike Hamad1, Kavita Babu2, Vikhyat S Bebarta3,4,5.   

Abstract

Cyanide toxicity is common after significant smoke inhalation. Two cases are presented that provide framework for the discussion of epidemiology, pathogenesis, presenting signs and symptoms, and treatment options of inhalational cyanide poisoning. An evidence-based algorithm is proposed that utilizes point-of-care testing to help physicians identify patients who benefit most from antidotal therapy.

Entities:  

Keywords:  Cyanide; Fire; Hydroxocobalamin; Smoke inhalation; Sodium thiosulfate

Mesh:

Substances:

Year:  2016        PMID: 26831054      PMCID: PMC4880610          DOI: 10.1007/s13181-016-0533-0

Source DB:  PubMed          Journal:  J Med Toxicol        ISSN: 1556-9039


  40 in total

1.  Acute cyanide poisoning.

Authors:  Stacie B Peddy; Mark R Rigby; Donald H Shaffner
Journal:  Pediatr Crit Care Med       Date:  2006-01       Impact factor: 3.624

2.  Focus on smoke inhalation--the most common cause of acute cyanide poisoning.

Authors:  Marc Eckstein; Paul M Maniscalco
Journal:  Prehosp Disaster Med       Date:  2006 Mar-Apr       Impact factor: 2.040

3.  The lack of transplacental movement of the cyanide antidote thiosulfate in gravid ewes.

Authors:  K A Graeme; S C Curry; D S Bikin; F A Lo Vecchio; T A Brandon
Journal:  Anesth Analg       Date:  1999-12       Impact factor: 5.108

4.  Cyanide poisoning by fire smoke inhalation: a European expert consensus.

Authors:  Kurt Anseeuw; Nicolas Delvau; Guillermo Burillo-Putze; Fabio De Iaco; Götz Geldner; Peter Holmström; Yves Lambert; Marc Sabbe
Journal:  Eur J Emerg Med       Date:  2013-02       Impact factor: 2.799

5.  Acute cyanide intoxication and central transmitter systems.

Authors:  S A Persson; G Cassel; A Sellström
Journal:  Fundam Appl Toxicol       Date:  1985-12

6.  Prevalence of hydrogen cyanide and carboxyhaemoglobin in victims of smoke inhalation during enclosed-space fires: a combined toxicological risk.

Authors:  Teresa Grabowska; Rafał Skowronek; Joanna Nowicka; Halina Sybirska
Journal:  Clin Toxicol (Phila)       Date:  2012-08-10       Impact factor: 4.467

7.  Patterns of cyanide antidote use since regulatory approval of hydroxocobalamin in the United States.

Authors:  Matthew J Streitz; Vikhyat S Bebarta; Douglas J Borys; David L Morgan
Journal:  Am J Ther       Date:  2014 Jul-Aug       Impact factor: 2.688

Review 8.  [Acute poisoning with carbon monoxide (CO) and cyanide (CN)].

Authors:  Frédéric J Baud
Journal:  Ther Umsch       Date:  2009-05

9.  Value of lactic acidosis in the assessment of the severity of acute cyanide poisoning.

Authors:  Frédéric J Baud; Stephen W Borron; Bruno Mégarbane; Hervé Trout; Frédéric Lapostolle; Eric Vicaut; Marcel Debray; Chantal Bismuth
Journal:  Crit Care Med       Date:  2002-09       Impact factor: 7.598

10.  The clinical experience of acute cyanide poisoning.

Authors:  D Yen; J Tsai; L M Wang; W F Kao; S C Hu; C H Lee; J F Deng
Journal:  Am J Emerg Med       Date:  1995-09       Impact factor: 2.469

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  3 in total

Review 1.  Carbon Monoxide and Cyanide Poisoning in the Burned Pregnant Patient: An Indication for Hyperbaric Oxygen Therapy.

Authors:  Derek M Culnan; Beretta Craft-Coffman; Genevieve H Bitz; Karel D Capek; Yiji Tu; William C Lineaweaver; Maggie J Kuhlmann-Capek
Journal:  Ann Plast Surg       Date:  2018-03       Impact factor: 1.539

2.  Toxic inhalational injury.

Authors:  Victoria Davies; Jake Turner; Michael Greenway
Journal:  BMJ Case Rep       Date:  2020-03-10

3.  Modest and variable efficacy of pre-exposure hydroxocobalamin and dicobalt edetate in a porcine model of acute cyanide salt poisoning.

Authors:  Adrian Thompson; Michael Dunn; Robert D Jefferson; Kosala Dissanayake; Frances Reed; Rachael Gregson; Stephen Greenhalgh; R Eddie Clutton; Peter G Blain; Simon Hl Thomas; Michael Eddleston
Journal:  Clin Toxicol (Phila)       Date:  2019-08-07       Impact factor: 4.467

  3 in total

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