Literature DB >> 26829621

Training the next generation of biomedical investigators in glycosciences.

Peter Agre, Carolyn Bertozzi, Mina Bissell, Kevin P Campbell, Richard D Cummings, Umesh R Desai, Mary Estes, Terence Flotte, Guy Fogleman, Fred Gage, David Ginsburg, Jeffrey I Gordon, Gerald Hart, Vincent Hascall, Laura Kiessling, Stuart Kornfeld, John Lowe, John Magnani, Lara K Mahal, Ruslan Medzhitov, Richard J Roberts, Robert Sackstein, Rita Sarkar, Ronald Schnaar, Nancy Schwartz, Ajit Varki, David Walt, Irving Weissman.   

Abstract

This position statement originated from a working group meeting convened on April 15, 2015, by the NHLBI and incorporates follow-up contributions by the participants as well as other thought leaders subsequently consulted, who together represent research fields relevant to all branches of the NIH. The group was deliberately composed not only of individuals with a current research emphasis in the glycosciences, but also of many experts from other fields, who evinced a strong interest in being involved in the discussions. The original goal was to discuss the value of creating centers of excellence for training the next generation of biomedical investigators in the glycosciences. A broader theme that emerged was the urgent need to bring the glycosciences back into the mainstream of biology by integrating relevant education into the curricula of medical, graduate, and postgraduate training programs, thus generating a critical sustainable workforce that can advance the much-needed translation of glycosciences into a more complete understanding of biology and the enhanced practice of medicine.

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Mesh:

Year:  2016        PMID: 26829621      PMCID: PMC4731185          DOI: 10.1172/JCI85905

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


  11 in total

1.  The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies.

Authors:  Peter Jandus; Kayluz Frias Boligan; David F Smith; Elisabeth de Graauw; Bodo Grimbacher; Camilla Jandus; Mai M Abdelhafez; Alain Despont; Nicolai Bovin; Dagmar Simon; Robert Rieben; Hans-Uwe Simon; Richard D Cummings; Stephan von Gunten
Journal:  Blood       Date:  2019-11-28       Impact factor: 22.113

2.  A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis.

Authors:  Praveen Agrawal; Barbara Fontanals-Cirera; Elena Sokolova; Samson Jacob; Christopher A Vaiana; Diana Argibay; Veronica Davalos; Meagan McDermott; Shruti Nayak; Farbod Darvishian; Mireia Castillo; Beatrix Ueberheide; Iman Osman; David Fenyö; Lara K Mahal; Eva Hernando
Journal:  Cancer Cell       Date:  2017-06-12       Impact factor: 31.743

3.  Fluoride Migration Catalysis Enables Simple, Stereoselective, and Iterative Glycosylation.

Authors:  Girish C Sati; Joshua L Martin; Yishu Xu; Tanmay Malakar; Paul M Zimmerman; John Montgomery
Journal:  J Am Chem Soc       Date:  2020-04-01       Impact factor: 15.419

Review 4.  Glycosylation in health and disease.

Authors:  Colin Reily; Tyler J Stewart; Matthew B Renfrow; Jan Novak
Journal:  Nat Rev Nephrol       Date:  2019-06       Impact factor: 42.439

Review 5.  Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey.

Authors:  Mengmeng Wang; Jianhui Zhu; David M Lubman; Chunfang Gao
Journal:  Clin Chem Lab Med       Date:  2019-03-26       Impact factor: 8.490

Review 6.  Biological roles of glycans.

Authors:  Ajit Varki
Journal:  Glycobiology       Date:  2016-08-24       Impact factor: 4.313

7.  A Cartography of Siglecs and Sialyltransferases in Gynecologic Malignancies: Is There a Road Towards a Sweet Future?

Authors:  Quentin Haas; Cedric Simillion; Stephan von Gunten
Journal:  Front Oncol       Date:  2018-03-13       Impact factor: 6.244

8.  Programmed cell removal by calreticulin in tissue homeostasis and cancer.

Authors:  Mingye Feng; Kristopher D Marjon; Fangfang Zhu; Rachel Weissman-Tsukamoto; Aaron Levett; Katie Sullivan; Kevin S Kao; Maxim Markovic; Paul A Bump; Hannah M Jackson; Timothy S Choi; Jing Chen; Allison M Banuelos; Jie Liu; Phung Gip; Lei Cheng; Denong Wang; Irving L Weissman
Journal:  Nat Commun       Date:  2018-08-10       Impact factor: 14.919

Review 9.  Life is sweet: the cell biology of glycoconjugates.

Authors:  Alex C Broussard; Michael Boyce
Journal:  Mol Biol Cell       Date:  2019-03-01       Impact factor: 4.138

10.  Assembly of Divalent Ligands and Their Effect on Divalent Binding to Pseudomonas aeruginosa Lectin LecA.

Authors:  Guangyun Yu; Anna Chiara Vicini; Roland J Pieters
Journal:  J Org Chem       Date:  2019-02-11       Impact factor: 4.354

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