Literature DB >> 26828239

Mallotojaponins B and C: Total Synthesis, Antiparasitic Evaluation, and Preliminary SAR Studies.

Tatyana D Grayfer1, Philippe Grellier2, Elisabeth Mouray2, Robert H Dodd1, Joëlle Dubois1, Kevin Cariou1.   

Abstract

The first total syntheses of mallotojaponin B and C as well as several analogues have been achieved. Biological evaluation of the synthesized compounds against Plasmodium falciparum and Trypanosoma brucei have also been carried out.

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Year:  2016        PMID： 26828239     DOI： 10.1021/acs.orglett.5b03676

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity.

Authors:  Dionissia A Pepe; Dimitra Toumpa; Christiane André-Barrès; Christophe Menendez; Elisabeth Mouray; Michel Baltas; Philippe Grellier; Dionissios Papaioannou; Constantinos M Athanassopoulos
Journal:  ACS Med Chem Lett       Date:  2020-03-24       Impact factor: 4.345

Review 2.  Progress of isolation, chemical synthesis and biological activities of natural chalcones bearing 2-hydroxy-3-methyl-3-butenyl group.

Authors:  Jiadai Zhai; Bingxia Sun; Feng Sang
Journal:  Front Chem       Date:  2022-08-15       Impact factor: 5.545

3.  Synthesis and Antimalarial Activity of Mallatojaponin C and Related Compounds.

Authors:  Alexander L Eaton; Seema Dalal; M Belen Cassera; Shuqi Zhao; David G I Kingston
Journal:  J Nat Prod       Date:  2016-05-26       Impact factor: 4.050

4.  Rottlerin: Structure Modifications and KCNQ1/KCNE1 Ion Channel Activity.

Authors:  Marco Lübke; Julian A Schreiber; Thang Le Quoc; Florian Körber; Jasmin Müller; Sivatharushan Sivanathan; Veronika Matschke; Janina Schubert; Nathalie Strutz-Seebohm; Guiscard Seebohm; Jürgen Scherkenbeck
Journal:  ChemMedChem       Date:  2020-05-05       Impact factor: 3.466

Review 5.  An overview on natural farnesyltransferase inhibitors for efficient cancer therapy.

Authors:  Xiaohan Dai; Yingni Sun; Ting Zhang; Yongfei Ming; Gao Hongwei
Journal:  J Enzyme Inhib Med Chem       Date:  2020-12       Impact factor: 5.051
  5 in total

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