| Literature DB >> 26826733 |
Liziane M B Morandini1, Alexandre T Neto1, Marcelo Pedroso1, Zaida I Antoniolli2, Robert A Burrow1, Adailton J Bortoluzzi3, Marco A Mostardeiro1, Ubiratan F da Silva1, Ionara I Dalcol1, Ademir F Morel4.
Abstract
Two lanostane triterpenoids (sclerodols A and B) were isolated from the culture of the Eucalyptus grandis derived from the endophyte Scleroderma UFSM Sc1(Persoon) Fries together with three known compounds: one related triterpenoid lanosta-8,23-dien-3β,25-diol, the disaccharide α,β-trehalose, and the sugar alcohol mannitol. Their structures were elucidated on the basis of 2D NMR, HRME, and single-crystal X-ray diffraction data. The methanol crude extract and the isolated lanostane triterpenoids showed promising anticandidal activities.Entities:
Keywords: Anticandidal activity; Fungal endophyte; Lanostenoids; Scleroderma UFSMSc1 (Persoon) Fries
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Year: 2016 PMID： 26826733 DOI： 10.1016/j.bmcl.2016.01.044
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823