| Literature DB >> 26824762 |
Hideki Yagi, Bisei Ohkawara, Hiroaki Nakashima, Kenyu Ito, Mikito Tsushima, Hisao Ishii, Kimitoshi Noto, Kyotaro Ohta, Akio Masuda, Shiro Imagama, Naoki Ishiguro, Kinji Ohno.
Abstract
Entities:
Year: 2016 PMID: 26824762 PMCID: PMC4732597 DOI: 10.1371/journal.pone.0148470
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Fig 4Zonisamide rescues cell death due to oxidative stress.
Primary motor neurons in DMEM/F12 with 0.5% FBS were treated with variable concentrations of zonisamide. After 1 h, cells were exposed to 100 μM hydrogen peroxide (H2O2) for 24 h. The number of viable cells was estimated by the MTS assay and was normalized to that without H2O2 (control). Mean and SE are indicated (n = 6). *p < 0.05 by one-way ANOVA followed by Tukey HSD.