Literature DB >> 26824762

Correction: Zonisamide Enhances Neurite Elongation of Primary Motor Neurons and Facilitates Peripheral Nerve Regeneration In Vitro and in a Mouse Model.

Hideki Yagi, Bisei Ohkawara, Hiroaki Nakashima, Kenyu Ito, Mikito Tsushima, Hisao Ishii, Kimitoshi Noto, Kyotaro Ohta, Akio Masuda, Shiro Imagama, Naoki Ishiguro, Kinji Ohno.   

Abstract

Entities:  

Year:  2016        PMID: 26824762      PMCID: PMC4732597          DOI: 10.1371/journal.pone.0148470

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


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Fig 4 is incorrect. The authors have provided a corrected version here.
Fig 4

Zonisamide rescues cell death due to oxidative stress.

Primary motor neurons in DMEM/F12 with 0.5% FBS were treated with variable concentrations of zonisamide. After 1 h, cells were exposed to 100 μM hydrogen peroxide (H2O2) for 24 h. The number of viable cells was estimated by the MTS assay and was normalized to that without H2O2 (control). Mean and SE are indicated (n = 6). *p < 0.05 by one-way ANOVA followed by Tukey HSD.

Zonisamide rescues cell death due to oxidative stress.

Primary motor neurons in DMEM/F12 with 0.5% FBS were treated with variable concentrations of zonisamide. After 1 h, cells were exposed to 100 μM hydrogen peroxide (H2O2) for 24 h. The number of viable cells was estimated by the MTS assay and was normalized to that without H2O2 (control). Mean and SE are indicated (n = 6). *p < 0.05 by one-way ANOVA followed by Tukey HSD.
  1 in total

1.  Zonisamide Enhances Neurite Elongation of Primary Motor Neurons and Facilitates Peripheral Nerve Regeneration In Vitro and in a Mouse Model.

Authors:  Hideki Yagi; Bisei Ohkawara; Hiroaki Nakashima; Kenyu Ito; Mikito Tsushima; Hisao Ishii; Kimitoshi Noto; Kyotaro Ohta; Akio Masuda; Shiro Imagama; Naoki Ishiguro; Kinji Ohno
Journal:  PLoS One       Date:  2015-11-16       Impact factor: 3.240

  1 in total

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