Literature DB >> 26824005

Autologous Fat Grafting in Severe Lower Extremity Asymmetries: Report of Four Cases.

Juan Monreal1.   

Abstract

BACKGROUND: Lower extremity asymmetries are challenging problems in plastic and aesthetic surgery practice. Regardless of their origin, atrophies and asymmetries can be extremely varied and difficult to solve with simple techniques.
OBJECTIVES: The author reports his experience in the treatment of four patients suffering from severe lower extremity atrophy and asymmetry of different etiologies with autologous fat grafting.
METHODS: A total of four cases are presented. Patient selection was based on the severity of atrophy and asymmetry. Two patients were treated with two sessions of simple fat grafting and two patients with one session of cell-enriched fat grafting. The end point in each session was determined by tension/blanching of soft tissues. All patients were followed up for at least 12 months after the last session. During the postoperative follow-up, variables, such as objective volume improvement, objective girth loss, return to daily activities, and patient satisfaction, were analyzed.
RESULTS: The initial analysis of postoperative results showed a good patient satisfaction rate with no relevant complications and an early return to daily activities. Estimated mean volume improvement for simple fat grafting cases was estimated as 44% after two treatments. Mean volume improvement in cell-enriched fat grafting cases was estimated as 25% after only one treatment.
CONCLUSIONS: Autologous fat grafting is a safe, effective, and reliable technique to perform aesthetic and reconstructive reshaping of a lower extremity in cases of atrophy or severe asymmetry. Depending on the preoperative soft tissue compliance, cell-assisted fat grafting will play an important role in reducing the number of sessions to perform.

Entities:  

Keywords:  fat grafting; human adipose tissue; lower extremity reconstruction; mesenchymal stem/stromal cells; reconstruction; stromal vascular fraction

Year:  2015        PMID: 26824005      PMCID: PMC4725679          DOI: 10.7759/cureus.402

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  14 in total

Review 1.  Fat grafting versus adipose-derived stem cell therapy: distinguishing indications, techniques, and outcomes.

Authors:  Christina J Tabit; Ginger C Slack; Kenneth Fan; Derrick C Wan; James P Bradley
Journal:  Aesthetic Plast Surg       Date:  2011-11-09       Impact factor: 2.326

Review 2.  Do Stem Cells Have an Effect When We Fat Graft?

Authors:  Brian D Rinker; Krishna S Vyas
Journal:  Ann Plast Surg       Date:  2016-06       Impact factor: 1.539

3.  Cell-assisted lipotransfer: supportive use of human adipose-derived cells for soft tissue augmentation with lipoinjection.

Authors:  Daisuke Matsumoto; Katsujiro Sato; Koichi Gonda; Yasuyuki Takaki; Tomokuni Shigeura; Takahiro Sato; Emiko Aiba-Kojima; Fumiko Iizuka; Keita Inoue; Hirotaka Suga; Kotaro Yoshimura
Journal:  Tissue Eng       Date:  2006-12

4.  Deepithelialized vertical rectus abdominis flap in calf augmentation.

Authors:  H D Axmann; W Schneider
Journal:  Aesthetic Plast Surg       Date:  1997 Jan-Feb       Impact factor: 2.326

5.  Successful filling of atrophic calf of leg with a dermal-fat graft. Case report.

Authors:  F Crocenzi
Journal:  Plast Reconstr Surg       Date:  1972-03       Impact factor: 4.730

6.  Calf augmentation using free TRAM flap.

Authors:  K C Hui; F Zhang; L Greenberg; W C Lineaweaver
Journal:  Microsurgery       Date:  1999       Impact factor: 2.425

7.  Fat grafting of the buttocks and lower limbs.

Authors:  L H Pereira; H N Radwanski
Journal:  Aesthetic Plast Surg       Date:  1996 Sep-Oct       Impact factor: 2.326

8.  Calf Augmentation and Reshaping with Autologous Fat Grafting.

Authors:  Gerhard S Mundinger; James E Vogel
Journal:  Aesthet Surg J       Date:  2015-09-01       Impact factor: 4.283

9.  Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells.

Authors:  Gino Rigotti; Alessandra Marchi; Mirco Galiè; Guido Baroni; Donatella Benati; Mauro Krampera; Annalisa Pasini; Andrea Sbarbati
Journal:  Plast Reconstr Surg       Date:  2007-04-15       Impact factor: 4.730

10.  Cell-assisted lipotransfer for cosmetic breast augmentation: supportive use of adipose-derived stem/stromal cells.

Authors:  Kotaro Yoshimura; Katsujiro Sato; Noriyuki Aoi; Masakazu Kurita; Toshitsugu Hirohi; Kiyonori Harii
Journal:  Aesthetic Plast Surg       Date:  2007-09-01       Impact factor: 2.326

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