Literature DB >> 2682327

Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases.

F Hefti1, J Hartikka, B Knusel.   

Abstract

This review summarizes the current knowledge of characterized neurotrophic factors, including nerve growth factor (NGF) which serves as paradigmatic example when studying novel molecules. Special consideration is given to the function of neurotrophic factors in the adult and aging brain. Strategies are discussed for the eventual development of pharmacological applications of these molecules in the treatment of neurodegenerative diseases.

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Year:  1989        PMID: 2682327     DOI: 10.1016/0197-4580(89)90118-8

Source DB:  PubMed          Journal:  Neurobiol Aging        ISSN: 0197-4580            Impact factor:   4.673


  42 in total

Review 1.  Regulation of ion channel expression in neural cells by hormones and growth factors.

Authors:  L J Chew; V Gallo
Journal:  Mol Neurobiol       Date:  1998-12       Impact factor: 5.590

Review 2.  Neurotrophins: roles in neuronal development and function.

Authors:  E J Huang; L F Reichardt
Journal:  Annu Rev Neurosci       Date:  2001       Impact factor: 12.449

3.  Immortal rat hippocampal cell lines exhibit neuronal and glial lineages and neurotrophin gene expression.

Authors:  E M Eves; M S Tucker; J D Roback; M Downen; M R Rosner; B H Wainer
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-15       Impact factor: 11.205

4.  Neurotrophic factors in neurodegenerative disorders: model of Parkinson's disease.

Authors:  J Garcia de Yebenes; J Yebenes; M A Mena
Journal:  Neurotox Res       Date:  2000       Impact factor: 3.911

5.  Neuroprotection in Alzheimer's disease - new strategies for treatment.

Authors:  A Nordberg
Journal:  Neurotox Res       Date:  2000       Impact factor: 3.911

6.  Neuroprotective and neurorestorative strategies for neuronal injury.

Authors:  M F Beal; T Palomo; R M Kostrzewa; T Archer
Journal:  Neurotox Res       Date:  2000       Impact factor: 3.911

7.  Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise.

Authors:  Catharine H Duman; Lee Schlesinger; Rosemarie Terwilliger; David S Russell; Samuel S Newton; Ronald S Duman
Journal:  Behav Brain Res       Date:  2008-11-14       Impact factor: 3.332

8.  Sonic Hedgehog Protein : A Novel Approach to the Treatment of Neurodegenerative Disorders?

Authors:  K Pang; T D Ingolia
Journal:  CNS Drugs       Date:  1998-04       Impact factor: 5.749

Review 9.  Neurotrophic factors for the investigation and treatment of movement disorders.

Authors:  Justo Garcia De Yébenes; Marina Sánchez; Maria Angeles Mena
Journal:  Neurotox Res       Date:  2003       Impact factor: 3.911

10.  Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo.

Authors:  T Hagg; S Varon
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

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