Literature DB >> 26821090

Rh(III)-Catalyzed Redox-Neutral Annulation of Primary Benzamides with Diazo Compounds: Approach to Isoquinolinones.

Youzhi Wu1, Peng Sun1, Kaifan Zhang1, Tie Yang1, Hequan Yao1, Aijun Lin1.   

Abstract

Reported herein is a Rh-catalyzed redox-neutral annulation of primary benzamides with diazo compounds, representing an efficient and economic protocol to isoquinolinones. The procedure exhibited good functional group tolerability, scalability, and regioselectivity, obviating the need for oxidants, and only environmentally benign N2 and H2O were released. Further utilization of the method provided an alternative route to functionalized isoquinolines.

Entities:  

Year:  2016        PMID： 26821090     DOI： 10.1021/acs.joc.5b02824

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Synthesis of [5,6]-Bicyclic Heterocycles with a Ring-Junction Nitrogen Atom: Rhodium(III)-Catalyzed C-H Functionalization of Alkenyl Azoles.

Authors:  Kim Søholm Halskov; Howard S Roth; Jonathan A Ellman
Journal:  Angew Chem Int Ed Engl       Date:  2017-07-05       Impact factor: 15.336

2.  One-pot construction of diverse and functionalized isochromenoquinolinediones by Rh(iii)-catalyzed annulation of unprotected arylamides with 3-diazoquinolinediones and their application for fluorescence sensor.

Authors:  Rajeev Shrestha; Hari Datta Khanal; Yong Rok Lee
Journal:  RSC Adv       Date:  2019-06-03       Impact factor: 3.361

3.  Combining the Ugi-azide multicomponent reaction and rhodium(III)-catalyzed annulation for the synthesis of tetrazole-isoquinolone/pyridone hybrids.

Authors:  Gerardo M Ojeda; Prabhat Ranjan; Pavel Fedoseev; Lisandra Amable; Upendra K Sharma; Daniel G Rivera; Erik V Van der Eycken
Journal:  Beilstein J Org Chem       Date:  2019-10-16       Impact factor: 2.883
  3 in total

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