Literature DB >> 26819198

New therapeutic approaches for the treatment of obesity.

Alan R Saltiel1.   

Abstract

This review discusses current and future pharmacological approaches to the treatment of obesity, with a focus on the biological control of energy balance.
Copyright © 2016, American Association for the Advancement of Science.

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Year:  2016        PMID: 26819198     DOI: 10.1126/scitranslmed.aad1811

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN: 1946-6234            Impact factor:   17.956


  35 in total

1.  Oral ionic liquid for the treatment of diet-induced obesity.

Authors:  Md Nurunnabi; Kelly N Ibsen; Eden E L Tanner; Samir Mitragotri
Journal:  Proc Natl Acad Sci U S A       Date:  2019-11-25       Impact factor: 11.205

2.  DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway.

Authors:  Juli Bai; Christopher Cervantes; Juan Liu; Sijia He; Haiyan Zhou; Bilin Zhang; Huan Cai; Dongqing Yin; Derong Hu; Zhi Li; Hongzhi Chen; Xiaoli Gao; Fang Wang; Jason C O'Connor; Yong Xu; Meilian Liu; Lily Q Dong; Feng Liu
Journal:  Proc Natl Acad Sci U S A       Date:  2017-10-30       Impact factor: 11.205

Review 3.  Mechanisms of Insulin Action and Insulin Resistance.

Authors:  Max C Petersen; Gerald I Shulman
Journal:  Physiol Rev       Date:  2018-10-01       Impact factor: 37.312

4.  Systematic Data Mining Reveals Synergistic H3R/MCHR1 Ligands.

Authors:  David Schaller; Stefanie Hagenow; Gina Alpert; Alexandra Naß; Robert Schulz; Marcel Bermudez; Holger Stark; Gerhard Wolber
Journal:  ACS Med Chem Lett       Date:  2017-05-04       Impact factor: 4.345

Review 5.  Role of Inactivity in Chronic Diseases: Evolutionary Insight and Pathophysiological Mechanisms.

Authors:  Frank W Booth; Christian K Roberts; John P Thyfault; Gregory N Ruegsegger; Ryan G Toedebusch
Journal:  Physiol Rev       Date:  2017-10-01       Impact factor: 37.312

6.  Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes.

Authors:  Xinmin Gan; Michael W Wilson; Tyler S Beyett; Bo Wen; Duxin Sun; Scott D Larsen; John J G Tesmer; Alan R Saltiel; Hollis D Showalter
Journal:  J Labelled Comp Radiopharm       Date:  2019-04-03       Impact factor: 1.921

7.  Adropin and glucagon-like peptide-2 are associated with glucose metabolism in obese children.

Authors:  Rui-Min Chen; Xin Yuan; Qian Ouyang; Xiang-Quan Lin; Zhuan-Zhuan Ai; Ying Zhang; Xiao-Hong Yang
Journal:  World J Pediatr       Date:  2019-10-10       Impact factor: 2.764

8.  Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition.

Authors:  Tyler S Beyett; Xinmin Gan; Shannon M Reilly; Louise Chang; Andrew V Gomez; Alan R Saltiel; Hollis D Showalter; John J G Tesmer
Journal:  Mol Pharmacol       Date:  2018-08-06       Impact factor: 4.436

9.  Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr-/- mice.

Authors:  Amy C Burke; Brian G Sutherland; Dawn E Telford; Marisa R Morrow; Cynthia G Sawyez; Jane Y Edwards; Maria Drangova; Murray W Huff
Journal:  J Lipid Res       Date:  2018-07-15       Impact factor: 5.922

Review 10.  The role of adipose tissue in cancer-associated cachexia.

Authors:  Janina A Vaitkus; Francesco S Celi
Journal:  Exp Biol Med (Maywood)       Date:  2016-12-08
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