Ignacio Conget1, Dalia Ávila2, Marga Giménez3, Carmen Quiros3, Vanesa Salaverria4, Belen Dueñas4. 1. Diabetes Unit. Endocrinology and Nutrition, IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Hospital Clínic i Universitari, Barcelona, Spain. Electronic address: iconget@clinic.ub.es. 2. Endocrinology and Nutrition Department, Health Services Center, University of León, León, Spain. 3. Diabetes Unit. Endocrinology and Nutrition, IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Hospital Clínic i Universitari, Barcelona, Spain. 4. Fundación para la Diabetes, Madrid, Diabetes Unit, Spain.
Abstract
OBJECTIVE: To assess the frequency of impaired awareness of hypoglycaemia (IAH) using a specific questionnaire (Spanish version) in a free access diabetes-related web site. METHODS: Data from a free access Spanish version of the Clarke test previously uploaded to the website of the Fundación para la Diabetes (March 2014-January 2015) were assessed. In addition to the eight questions in Clarke's questionnaire, information on type of diabetes, age, and disease duration was obtained. The Clarke test divided participants into three categories: normal awareness, uncertain and IAH. RESULTS: Of the 418 participants with type 1 diabetes, 51.2% were aged 36-55 years. In 34.7%, diabetes had been diagnosed >15 years before, while disease duration was <2 years in 11%. According to Clarke categories, 23.4% had IAH, 15.3% uncertain awareness, and 61.3% normal awareness. The longer the duration of diabetes, the higher the Clarke test score. According to the Clarke test, 14.1% of participants had experienced at least one episode of severe hypoglycaemia in the previous year, and half of these (7.4%) had suffered severe hypoglycaemia two or more times. All but one of the participants with two or more episodes of severe hypoglycaemia had IAH. CONCLUSIONS: Our study shows that the rate of IAH using an online survey is similar (25%) to that previously reported in other geographical areas, increases with diabetes duration, and identifies subjects prone to severe hypoglycaemia.
OBJECTIVE: To assess the frequency of impaired awareness of hypoglycaemia (IAH) using a specific questionnaire (Spanish version) in a free access diabetes-related web site. METHODS: Data from a free access Spanish version of the Clarke test previously uploaded to the website of the Fundación para la Diabetes (March 2014-January 2015) were assessed. In addition to the eight questions in Clarke's questionnaire, information on type of diabetes, age, and disease duration was obtained. The Clarke test divided participants into three categories: normal awareness, uncertain and IAH. RESULTS: Of the 418 participants with type 1 diabetes, 51.2% were aged 36-55 years. In 34.7%, diabetes had been diagnosed >15 years before, while disease duration was <2 years in 11%. According to Clarke categories, 23.4% had IAH, 15.3% uncertain awareness, and 61.3% normal awareness. The longer the duration of diabetes, the higher the Clarke test score. According to the Clarke test, 14.1% of participants had experienced at least one episode of severe hypoglycaemia in the previous year, and half of these (7.4%) had suffered severe hypoglycaemia two or more times. All but one of the participants with two or more episodes of severe hypoglycaemia had IAH. CONCLUSIONS: Our study shows that the rate of IAH using an online survey is similar (25%) to that previously reported in other geographical areas, increases with diabetes duration, and identifies subjects prone to severe hypoglycaemia.
Authors: Martine J Wellens; Charlotte E Vollenbrock; Pim Dekker; Lianne S M Boesten; Petronella H Geelhoed-Duijvestijn; Martine M C de Vries-Velraeds; Giesje Nefs; Bruce H R Wolffenbuttel; Henk-Jan Aanstoot; Peter R van Dijk Journal: BMJ Open Diabetes Res Care Date: 2021-09
Authors: O Moser; H Ziko; H Elsayed; D A Hochfellner; T Pöttler; A Mueller; M L Eckstein; H Sourij; J K Mader Journal: Diabet Med Date: 2020-07-16 Impact factor: 4.359