Jitendra Rajendra Ingole1, Rishi Devilal Patel1, Sonali Jitendra Ingole2, Harshal Tukaram Pandave3. 1. Associate Professor, Department of Medicine, SKN Medical College , Narhe, Sinhgad Road, Pune, India . 2. Assistant Professor, Department of Obstetric and Gynecology, SKN Medical College , Narhe, Sinhgad Road, Pune, India . 3. Associate Professor, Department of PSM, SKN Medical College , Narhe, Sinhgad Road, Pune, India .
Abstract
INTRODUCTION: Vitamin B12 deficiency is mainly diagnosed in symptomatic patients. However, the deficiency may also be prevalent in asymptomatic patients. Our aim was to study the prevalence of Vit B12 deficiency in IT professionals (Information Technology Professionals from Software industry) who presented for routine health screening and to correlate the deficiency to various parameters. MATERIALS AND METHODS: This was single centre, observational study comprising of 84 IT professionals. The data was collected in structured format. The study was designed to identify prevalence of Vit B12 deficiency and correlate to other factors such as type of diet, income level & regular use of medication (such as Antacid & Metformin). RESULTS: Total 28 individuals were found to be deficient (33.34%). Prevalence of Vit B12 deficiency amongst Vegetarian and non vegetarian diet adhering subjects was 47.5% and 20.45% respectively. B12 deficiency was also prevalent in high income age group. Further chronic intake of PPI (Proton pump inhibitor) and Metformin was associated with prevalence of 37.5% and 33.34% in the present study. CONCLUSION: During health screening of IT Professionals, significant prevalence of Vit B12 deficiency was noted across all income groups & non vegetarian diet consuming subjects also. There is significant correlation between Vit B12 deficiency with chronic use of PPI and Metformin.
INTRODUCTION: Vitamin B12 deficiency is mainly diagnosed in symptomatic patients. However, the deficiency may also be prevalent in asymptomatic patients. Our aim was to study the prevalence of Vit B12 deficiency in IT professionals (Information Technology Professionals from Software industry) who presented for routine health screening and to correlate the deficiency to various parameters. MATERIALS AND METHODS: This was single centre, observational study comprising of 84 IT professionals. The data was collected in structured format. The study was designed to identify prevalence of Vit B12 deficiency and correlate to other factors such as type of diet, income level & regular use of medication (such as Antacid & Metformin). RESULTS: Total 28 individuals were found to be deficient (33.34%). Prevalence of Vit B12 deficiency amongst Vegetarian and non vegetarian diet adhering subjects was 47.5% and 20.45% respectively. B12 deficiency was also prevalent in high income age group. Further chronic intake of PPI (Proton pump inhibitor) and Metformin was associated with prevalence of 37.5% and 33.34% in the present study. CONCLUSION: During health screening of IT Professionals, significant prevalence of Vit B12 deficiency was noted across all income groups & non vegetarian diet consuming subjects also. There is significant correlation between Vit B12 deficiency with chronic use of PPI and Metformin.
Authors: David Coelho; Terttu Suormala; Martin Stucki; Jordan P Lerner-Ellis; David S Rosenblatt; Robert F Newbold; Matthias R Baumgartner; Brian Fowler Journal: N Engl J Med Date: 2008-04-03 Impact factor: 91.245