Literature DB >> 26816570

Surgical Management of Bulky Mediastinal Metastases in Follicular Thyroid Carcinoma.

Zainal Adwin1, Ayub Nur2, Shahrun Suhaimi2, Ramzisham Rahman2.   

Abstract

Follicular thyroid adenoma and carcinoma are very common. Benign and malignant lesions are usually indistinguishable from cytology alone and often require confirmatory resection. The spread of follicular carcinoma is usually hematogenous and is treated with surgery and adjuvant radioactive iodine. Very rarely, metastases occur in the mediastinum. Patients usually present with severe compressive symptoms. With proper treatment and follow-up, the prognosis for these type of thyroid malignancies is excellent. In the case presented here, our patient presented to the Universiti Kebangsaan Malaysia Medical Center with a progressively enlarging anterior neck swelling. The swelling had started 10 years before his presentation. We diagnosed him with an advanced thyroid malignancy with bulky mediastinal metastases. After extensive investigations and counseling, we chose to treat the patient with tumor excision and mediastinal metastases resection. Typically, mediastinal resection involves the removal of the sternum and use of an acrylic implant to recreate the sternum. In this case, the sternum and ribs were removed with subsequent myocutaneous flap coverage for the wound defect. Our experience represents an alternative treatment option in cases where implant use is unsuitable.

Entities:  

Keywords:  Follicular Thyroid Carcinoma; Free Tissue Flaps; Mediastinum; Thyroid Cancer

Year:  2016        PMID: 26816570      PMCID: PMC4720940          DOI: 10.5001/omj.2016.13

Source DB:  PubMed          Journal:  Oman Med J        ISSN: 1999-768X


  9 in total

1.  Recent advances in thyroid cancer.

Authors:  Elizabeth G Grubbs; Thereasa A Rich; Guojun Li; Erich M Sturgis; Maher N Younes; Jeffrey N Myers; Beth Edeiken-Monroe; Bruno D Fornage; Douglas P Monroe; Gregg A Staerkel; Michelle D Williams; Steven G Waguespack; Mimi I Hu; Gilbert Cote; Robert F Gagel; James Cohen; Randal S Weber; Daniel A Anaya; F Chris Holsinger; Nancy D Perrier; Gary L Clayman; Douglas B Evans
Journal:  Curr Probl Surg       Date:  2008-03       Impact factor: 1.909

2.  Deaths due to differentiated thyroid cancer: a 46-year perspective.

Authors:  J K Harness; M K McLeod; N W Thompson; W C Noble; R E Burney
Journal:  World J Surg       Date:  1988-10       Impact factor: 3.352

3.  Two cases of sternectomy for bone metastasis due to aggressive variants of thyroid papillary carcinoma.

Authors:  Kuauhyama Luna-Ortiz; Rosa Angélica Salcedo-Hernández; Leonardo Saúl Lino-Silva; Antonio Gómez-Pedraza
Journal:  Int J Surg Case Rep       Date:  2012-11-28

4.  Immediate causes of death in thyroid carcinoma: clinicopathological analysis of 161 fatal cases.

Authors:  Y Kitamura; K Shimizu; M Nagahama; K Sugino; O Ozaki; T Mimura; K Ito; K Ito; S Tanaka
Journal:  J Clin Endocrinol Metab       Date:  1999-11       Impact factor: 5.958

5.  Follicular variant of papillary thyroid carcinoma: a long-term follow-up.

Authors:  Christian Passler; Gerhard Prager; Christian Scheuba; Barbara E Niederle; Klaus Kaserer; Georg Zettinig; Bruno Niederle
Journal:  Arch Surg       Date:  2003-12

6.  A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995 [see commetns].

Authors:  S A Hundahl; I D Fleming; A M Fremgen; H R Menck
Journal:  Cancer       Date:  1998-12-15       Impact factor: 6.860

7.  Thyroid carcinoma metastasized to the sternum: resection of the sternum and reconstruction with acrylic resin.

Authors:  O Ozaki; W Kitagawa; H Koshiishi; K Sugino; T Mimura; K Ito
Journal:  J Surg Oncol       Date:  1995-12       Impact factor: 3.454

8.  Role of metastasectomy in the management of thyroid carcinoma: the NIH experience.

Authors:  Ho Pak; Loukas Gourgiotis; Wen-I Chang; Lori C Guthrie; Monica C Skarulis; James C Reynolds; Maria J Merino; David S Schrump; Steven K Libutti; H Richard Alexander; Nicholas J Sarlis
Journal:  J Surg Oncol       Date:  2003-01       Impact factor: 3.454

9.  Giant sternal metastasis secondary to follicular carcinoma of the thyroid gland: report of a case.

Authors:  Sotirios Moraitis; Apostolos Perelas; Levon Toufektzian; Nikolaos Mazarakis; Georgios Pechlivanides
Journal:  Surg Today       Date:  2012-05-11       Impact factor: 2.549

  9 in total
  1 in total

1.  Huge Pulsatile Sternal Mass.

Authors:  Nornazirah Azizan; Firdaus Hayati; Hui Lian Ho; Siti Zubaidah Sharif
Journal:  Oman Med J       Date:  2020-06-30
  1 in total

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